WormBase Tree Display for Gene: WBGene00004008
expand all nodes | collapse all nodes | view schema
| WBGene00004008 | SMap | S_parent | Sequence | F22E10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pgp-14 | Person_evidence | WBPerson490 | |||||
| Sequence_name | F22E10.3 | ||||||||
| Molecular_name | F22E10.3 | ||||||||
| F22E10.3.1 | |||||||||
| CE03262 | |||||||||
| Other_name | CELE_F22E10.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | pgp-14 | ||||||||
| DB_info | Database | AceView | gene | XN364 | |||||
| WormQTL | gene | WBGene00004008 | |||||||
| WormFlux | gene | WBGene00004008 | |||||||
| NDB | locus_tag | CELE_F22E10.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004008|UniProtKB=G5EG61 | |||||||
| family | PTHR24221 | ||||||||
| NCBI | gene | 181416 | |||||||
| RefSeq | protein | NM_077727.10 | |||||||
| TrEMBL | UniProtAcc | G5EG61 | |||||||
| UniProt_GCRP | UniProtAcc | G5EG61 | |||||||
| OMIM | gene | 171050 | |||||||
| 171060 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pgp | ||||||||
| Allele (62) | |||||||||
| Strain | WBStrain00001996 | ||||||||
| WBStrain00032692 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOPX110 | ||||||||
| Ortholog (53) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | pgp-14 encodes a member of the ABC transporter family with high similarity to the vertebrate MDR (multidrug resistance) family; PGP-14 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-14 activity via large-scale RNAi screens does not result in any obvious defects, the precise role of pgp-14 in C. elegans development and/or behavior is not yet known; pgp-14 promoter-gfp fusion proteins are expressed in larvae and adults in the anterior pharynx. | Paper_evidence | WBPaper00006421 | |||||
| WBPaper00006525 | |||||||||
| WBPaper00024561 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 07 Mar 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in response to nematicide. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB4 (ATP binding cassette subfamily B member 4); and ABCB5 (ATP binding cassette subfamily B member 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (39) | ||||||||
| Molecular_info | Corresponding_CDS | F22E10.3 | |||||||
| Corresponding_transcript | F22E10.3.1 | ||||||||
| Other_sequence | JI168113.1 | ||||||||
| JI235600.1 | |||||||||
| JI231282.1 | |||||||||
| JI164894.1 | |||||||||
| Acan_isotig21429 | |||||||||
| JI218053.1 | |||||||||
| CJC02657_1 | |||||||||
| ASC19568_1 | |||||||||
| JI241304.1 | |||||||||
| Associated_feature | WBsf238081 | ||||||||
| WBsf238082 | |||||||||
| WBsf238083 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00045324 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000347 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077361 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013753 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3326 | ||||||||
| Expr3327 | |||||||||
| Expr4618 | |||||||||
| Expr5828 | |||||||||
| Expr1031917 | |||||||||
| Expr1149248 | |||||||||
| Expr2014867 | |||||||||
| Expr2033102 | |||||||||
| Drives_construct | WBCnstr00002780 | ||||||||
| WBCnstr00011322 | |||||||||
| WBCnstr00011323 | |||||||||
| WBCnstr00012122 | |||||||||
| WBCnstr00035743 | |||||||||
| Construct_product | WBCnstr00035743 | ||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (235) | |||||||||
| Interaction | WBInteraction000031500 | ||||||||
| WBInteraction000184749 | |||||||||
| WBInteraction000187429 | |||||||||
| WBInteraction000197007 | |||||||||
| WBInteraction000199241 | |||||||||
| WBInteraction000210515 | |||||||||
| WBInteraction000210516 | |||||||||
| WBInteraction000238364 | |||||||||
| WBInteraction000257223 | |||||||||
| WBInteraction000280652 | |||||||||
| WBInteraction000281312 | |||||||||
| WBInteraction000282801 | |||||||||
| WBInteraction000304650 | |||||||||
| WBInteraction000307139 | |||||||||
| WBInteraction000312807 | |||||||||
| WBInteraction000324963 | |||||||||
| WBInteraction000347824 | |||||||||
| WBInteraction000352705 | |||||||||
| WBInteraction000371928 | |||||||||
| WBInteraction000393956 | |||||||||
| WBInteraction000402870 | |||||||||
| WBInteraction000413431 | |||||||||
| WBInteraction000418786 | |||||||||
| WBInteraction000423018 | |||||||||
| WBInteraction000437621 | |||||||||
| WBInteraction000453689 | |||||||||
| WBInteraction000465129 | |||||||||
| WBInteraction000469951 | |||||||||
| WBInteraction000472432 | |||||||||
| WBInteraction000474696 | |||||||||
| WBInteraction000549819 | |||||||||
| WBInteraction000549944 | |||||||||
| WBInteraction000552902 | |||||||||
| Map_info | Map | X | Position | 8.21375 | Error | 0.008856 | |||
| Positive | Positive_clone | F22E10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Sequence connection from [Sheps JA, Baillie DL] [040902 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
