WormBase Tree Display for Gene: WBGene00003980
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| WBGene00003980 | SMap | S_parent | Sequence | F09C3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pes-7 | Person_evidence | WBPerson266 | |||||
| Sequence_name | F09C3.1 | ||||||||
| Molecular_name | F09C3.1 | ||||||||
| F09C3.1.1 | |||||||||
| CE23636 | |||||||||
| Other_name | tag-2 | CGC_data_submission | |||||||
| CELE_F09C3.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | pes-7 | ||||||||
| DB_info | Database | AceView | gene | 1O861 | |||||
| WormQTL | gene | WBGene00003980 | |||||||
| WormFlux | gene | WBGene00003980 | |||||||
| NDB | locus_tag | CELE_F09C3.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003980|UniProtKB=O17772 | |||||||
| family | PTHR14149 | ||||||||
| NCBI | gene | 173294 | |||||||
| RefSeq | protein | NM_061091.6 | |||||||
| TREEFAM | TREEFAM_ID | TF313078 | |||||||
| TrEMBL | UniProtAcc | O17772 | |||||||
| UniProt_GCRP | UniProtAcc | O17772 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pes | ||||||||
| Allele (188) | |||||||||
| Legacy_information | [C.elegansII] NMK. pes-7: lacZ expressed in all ganglia,ventral nerve cord; predominantly nuclear,some in neurites, vulva, spermatheca. Staining from embryonic elongation onward.Clone UL#25C4, cosmid K04H8. [Young and Hope 1993; UL] | ||||||||
| Strain | WBStrain00002434 | ||||||||
| WBStrain00002313 | |||||||||
| WBStrain00035541 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00030664 | ||||||||
| 00030665 | |||||||||
| 00030666 | |||||||||
| 00030667 | |||||||||
| 00030668 | |||||||||
| 00030669 | |||||||||
| 00112108 | |||||||||
| Ortholog (44) | |||||||||
| Structured_description | Concise_description | pes-7 encodes an IQGAP ortholog; IQGAP proteins bind actin and CLIP-170,effect activities of the Rho family GTPases Rac1 and Cdc42, and functionin cytokinesis; PES-7 is required for completing meiosis and mitosis,and for germline formation and maintenance; IQGAP's alpha-actinin domainis related distantly to alpha-actinin domains in calponin, transgelin(SM22 alpha), and the proto-oncogene Vav; a pes-7 reporter is firstexpressed in the ventral nerve cord of the elongating embryo and inlater stages of development is also expressed in all major ganglia, thevulva, and in the spermathecal valves; in the ventral nerve cord, pes-7expression is detected in nuclei as well as in cell bodies and neuralprocesses. | Paper_evidence | WBPaper00003306 | |||||
| WBPaper00004402 | |||||||||
| WBPaper00012852 | |||||||||
| WBPaper00013096 | |||||||||
| WBPaper00013097 | |||||||||
| WBPaper00013311 | |||||||||
| WBPaper00024200 | |||||||||
| WBPaper00028841 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 11 Dec 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activator activity; actin filament binding activity; and calmodulin binding activity. Predicted to be involved in mitotic actomyosin contractile ring assembly actin filament organization. Predicted to be located in cell cortex. Expressed in ganglia; intestine; muscle cell; and tail. Is an ortholog of human IQGAP1 (IQ motif containing GTPase activating protein 1); IQGAP2 (IQ motif containing GTPase activating protein 2); and IQGAP3 (IQ motif containing GTPase activating protein 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F09C3.1 | |||||||
| Corresponding_transcript | F09C3.1.1 | ||||||||
| Other_sequence | Hbac_isotig03953 | ||||||||
| CGC01025_1 | |||||||||
| CJC07826_1 | |||||||||
| Associated_feature | WBsf716965 | ||||||||
| WBsf717600 | |||||||||
| WBsf986113 | |||||||||
| WBsf1011218 | |||||||||
| WBsf218782 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00080572 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00044088 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114788 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00080490 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00080486 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003345 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114642 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00002992 | ||||||||
| WBCnstr00004490 | |||||||||
| WBCnstr00035763 | |||||||||
| WBCnstr00041829 | |||||||||
| Construct_product | WBCnstr00035763 | ||||||||
| WBCnstr00041829 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (160) | |||||||||
| Interaction (102) | |||||||||
| Anatomy_function | WBbtf1081 | ||||||||
| WBbtf1086 | |||||||||
| WBbtf1087 | |||||||||
| WBbtf1088 | |||||||||
| Map_info | Map | I | Position | 24.1453 | Error | 0.021203 | |||
| Positive | Positive_clone | F09C3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4572 | |||||||
| 4793 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00001752 | ||||||||
| WBPaper00013425 | |||||||||
| WBPaper00024200 | |||||||||
| WBPaper00035198 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00045213 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059357 | |||||||||
| WBPaper00061547 | |||||||||
| Remark | Gene name created from parsing 'genotype' field from CGC strain information [krb 020721] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
