| WBGene00003980 | SMap | S_parent | Sequence | F09C3 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | pes-7 | Person_evidence | WBPerson266 |
| | | Sequence_name | F09C3.1 |
| | | Molecular_name | F09C3.1 |
| | | | F09C3.1.1 |
| | | | CE23636 |
| | | Other_name | tag-2 | CGC_data_submission |
| | | | CELE_F09C3.1 | Accession_evidence | NDB | BX284601 |
| | | Public_name | pes-7 |
| | DB_info | Database | AceView | gene | 1O861 |
| | | | WormQTL | gene | WBGene00003980 |
| | | | WormFlux | gene | WBGene00003980 |
| | | | NDB | locus_tag | CELE_F09C3.1 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00003980|UniProtKB=O17772 |
| | | | | family | PTHR14149 |
| | | | NCBI | gene | 173294 |
| | | | RefSeq | protein | NM_061091.6 |
| | | | TREEFAM | TREEFAM_ID | TF313078 |
| | | | TrEMBL | UniProtAcc | O17772 |
| | | | UniProt_GCRP | UniProtAcc | O17772 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | pes |
| | Allele (188) |
| | Legacy_information | [C.elegansII] NMK. pes-7: lacZ expressed in all ganglia,ventral nerve cord; predominantly nuclear,some in neurites, vulva, spermatheca. Staining from embryonic elongation onward.Clone UL#25C4, cosmid K04H8. [Young and Hope 1993; UL] |
| | Strain | WBStrain00002434 |
| | | WBStrain00002313 |
| | | WBStrain00035541 |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00030664 |
| | | 00030665 |
| | | 00030666 |
| | | 00030667 |
| | | 00030668 |
| | | 00030669 |
| | | 00112108 |
| | Ortholog (44) |
| | Structured_description | Concise_description | pes-7 encodes an IQGAP ortholog; IQGAP proteins bind actin and CLIP-170,effect activities of the Rho family GTPases Rac1 and Cdc42, and functionin cytokinesis; PES-7 is required for completing meiosis and mitosis,and for germline formation and maintenance; IQGAP's alpha-actinin domainis related distantly to alpha-actinin domains in calponin, transgelin(SM22 alpha), and the proto-oncogene Vav; a pes-7 reporter is firstexpressed in the ventral nerve cord of the elongating embryo and inlater stages of development is also expressed in all major ganglia, thevulva, and in the spermathecal valves; in the ventral nerve cord, pes-7expression is detected in nuclei as well as in cell bodies and neuralprocesses. | Paper_evidence | WBPaper00003306 |
| | | | | | WBPaper00004402 |
| | | | | | WBPaper00012852 |
| | | | | | WBPaper00013096 |
| | | | | | WBPaper00013097 |
| | | | | | WBPaper00013311 |
| | | | | | WBPaper00024200 |
| | | | | | WBPaper00028841 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 11 Dec 2006 00:00:00 |
| | | Automated_description | Predicted to enable GTPase activator activity; actin filament binding activity; and calmodulin binding activity. Predicted to be involved in mitotic actomyosin contractile ring assembly actin filament organization. Predicted to be located in cell cortex. Expressed in ganglia; intestine; muscle cell; and tail. Is an ortholog of human IQGAP1 (IQ motif containing GTPase activating protein 1); IQGAP2 (IQ motif containing GTPase activating protein 2); and IQGAP3 (IQ motif containing GTPase activating protein 3). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F09C3.1 |
| | Corresponding_transcript | F09C3.1.1 |
| | Other_sequence | Hbac_isotig03953 |
| | | CGC01025_1 |
| | | CJC07826_1 |
| | Associated_feature | WBsf716965 |
| | | WBsf717600 |
| | | WBsf986113 |
| | | WBsf1011218 |
| | | WBsf218782 |
| Experimental_info | RNAi_result | WBRNAi00080572 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00044088 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00114788 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080490 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080486 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00003345 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00114642 | Inferred_automatically | RNAi_primary |
| | Expr_pattern (12) |
| | Drives_construct | WBCnstr00002992 |
| | | WBCnstr00004490 |
| | | WBCnstr00035763 |
| | | WBCnstr00041829 |
| | Construct_product | WBCnstr00035763 |
| | | WBCnstr00041829 |
| | Microarray_results (19) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037682:sma-2_downregulated |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00037950:pharyngeal-muscle_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038061:aldicarb_downregulated |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00040285:H2S_12hr_downregulated |
| | | WBPaper00044426:rotenone_24h_downregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045417:128Q-huntingtin_downreglated |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h |
| | | WBPaper00047132:glp-1(ts)-25C_upregulated |
| | | WBPaper00048690:male-Z1-Z4-daughter_enriched |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00050015:ifg-1(RNAi)_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050496:unc-39(hp701)_regulated |
| | | WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00051039:ash-2(RNAi)_regulated_intestine |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051461:pig-1(gm344)_downregulated |
| | | WBPaper00051558:aging_regulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00055103:thoc-5(wy822)_upregulated |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055354:Psora-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_downregulated |
| | | WBPaper00055482:pmt-2(RNAi)_upregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056034:pals-25(jy9)_upregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056090:E.faecalis_upregulated_N2 |
| | | WBPaper00056139:soil-microbiota_upregulated |
| | | WBPaper00056471:S.aureus-4h_upregulated_N2 |
| | | WBPaper00056826:SGP_biased |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057006:DietaryRestriction_upregulated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00058958:100mGy-irradiation-72h_upregulated |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059566:wdr-23(mac32)_upregulated |
| | | WBPaper00059567:olrn-1(ums9)_regulated |
| | | WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059763:neuron_expressed |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060100:SiNP_upregulated_mRNA |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060459:bcat-1(RNAi)_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00060909:atfs-1(cmh15)_downregulated |
| | | WBPaper00061007:HB101_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:AIA |
| | | WBPaper00061340:AIZ |
| | | WBPaper00061340:AVA |
| | | WBPaper00061340:AVG |
| | | WBPaper00061340:AVL |
| | | WBPaper00061340:DA_DB |
| | | WBPaper00061340:PVT |
| | | WBPaper00061340:RIS |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:F54D5.3_7003-F54D5.3_7004 |
| | | WBPaper00061651:PVD_enriched |
| | | WBPaper00061902:camt-1(ok515)_regulated_RMG |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064156:lbp-3(overexpress)_upregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064933:bcf-1(ylf1)_downregulated_transcript |
| | | WBPaper00065158:AFD_enriched |
| | | WBPaper00065373:Cisplatin_downregulated_WT |
| | | WBPaper00065373:sek-1(km4)_downregulated_Ref |
| | | WBPaper00065373:sek-1(km4)_upregulated_cisplatin |
| | | WBPaper00065835:Day5_vs_Day1_downregulated |
| | | WBPaper00065841:70_0 |
| | | WBPaper00065841:70_1 |
| | | WBPaper00065841:124_0 |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14 |
| | | WBPaper00066232:ash-2(RNAi)_downregulated_WT |
| | | WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2 |
| | | cgc4489_group_1 |
| | | WBPaper00024393:strongly_regulated_dauer_genes |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:24hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_2 |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00036286:Pattern_C |
| | | WBPaper00038427:lin-54_embryo_changed |
| | | WBPaper00040210:Diazinon_24C_regulated |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00045263:0.1mM-paraquat_downregulated |
| | | WBPaper00045263:nuo-6(qm200)_downregulated |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00047070:N2_starvation_upregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc6390]:Cluster_B |
| | Interaction (102) |
| | Anatomy_function | WBbtf1081 |
| | | WBbtf1086 |
| | | WBbtf1087 |
| | | WBbtf1088 |
| Map_info | Map | I | Position | 24.1453 | Error | 0.021203 |
| | Positive | Positive_clone | F09C3 | Inferred_automatically | From CDS info |
| | | | | | From sequence, transcript, pseudogene data |
| | Mapping_data | Multi_point | 4572 |
| | | | 4793 |
| | Pseudo_map_position |
| Reference | WBPaper00001752 |
| | WBPaper00013425 |
| | WBPaper00024200 |
| | WBPaper00035198 |
| | WBPaper00038491 |
| | WBPaper00045213 |
| | WBPaper00055090 |
| | WBPaper00059357 |
| | WBPaper00061547 |
| Remark | Gene name created from parsing 'genotype' field from CGC strain information [krb 020721] |
| | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
