WormBase Tree Display for Gene: WBGene00003980
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WBGene00003980 | SMap | S_parent | Sequence | F09C3 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | pes | ||||||
Allele (188) | |||||||
Legacy_information | [C.elegansII] NMK. pes-7: lacZ expressed in all ganglia,ventral nerve cord; predominantly nuclear,some in neurites, vulva, spermatheca. Staining from embryonic elongation onward.Clone UL#25C4, cosmid K04H8. [Young and Hope 1993; UL] | ||||||
Strain | WBStrain00002434 | ||||||
WBStrain00002313 | |||||||
WBStrain00035541 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00030664 | ||||||
00030665 | |||||||
00030666 | |||||||
00030667 | |||||||
00030668 | |||||||
00030669 | |||||||
00112108 | |||||||
Ortholog (44) | |||||||
Structured_description | Concise_description | pes-7 encodes an IQGAP ortholog; IQGAP proteins bind actin and CLIP-170,effect activities of the Rho family GTPases Rac1 and Cdc42, and functionin cytokinesis; PES-7 is required for completing meiosis and mitosis,and for germline formation and maintenance; IQGAP's alpha-actinin domainis related distantly to alpha-actinin domains in calponin, transgelin(SM22 alpha), and the proto-oncogene Vav; a pes-7 reporter is firstexpressed in the ventral nerve cord of the elongating embryo and inlater stages of development is also expressed in all major ganglia, thevulva, and in the spermathecal valves; in the ventral nerve cord, pes-7expression is detected in nuclei as well as in cell bodies and neuralprocesses. | Paper_evidence | WBPaper00003306 | |||
WBPaper00004402 | |||||||
WBPaper00012852 | |||||||
WBPaper00013096 | |||||||
WBPaper00013097 | |||||||
WBPaper00013311 | |||||||
WBPaper00024200 | |||||||
WBPaper00028841 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 11 Dec 2006 00:00:00 | ||||||
Automated_description | Predicted to enable GTPase activator activity; actin filament binding activity; and calmodulin binding activity. Predicted to be involved in mitotic actomyosin contractile ring assembly actin filament organization. Predicted to be located in cell cortex. Expressed in ganglia; intestine; muscle cell; and tail. Is an ortholog of human IQGAP1 (IQ motif containing GTPase activating protein 1); IQGAP2 (IQ motif containing GTPase activating protein 2); and IQGAP3 (IQ motif containing GTPase activating protein 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F09C3.1 | |||||
Corresponding_transcript | F09C3.1.1 | ||||||
Other_sequence | Hbac_isotig03953 | ||||||
CGC01025_1 | |||||||
CJC07826_1 | |||||||
Associated_feature | WBsf716965 | ||||||
WBsf717600 | |||||||
WBsf986113 | |||||||
WBsf1011218 | |||||||
WBsf218782 | |||||||
Experimental_info | RNAi_result | WBRNAi00080572 | Inferred_automatically | RNAi_primary | |||
WBRNAi00044088 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00114788 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080490 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080486 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00003345 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00114642 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (12) | |||||||
Drives_construct | WBCnstr00002992 | ||||||
WBCnstr00004490 | |||||||
WBCnstr00035763 | |||||||
WBCnstr00041829 | |||||||
Construct_product | WBCnstr00035763 | ||||||
WBCnstr00041829 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (160) | |||||||
Interaction (102) | |||||||
Anatomy_function | WBbtf1081 | ||||||
WBbtf1086 | |||||||
WBbtf1087 | |||||||
WBbtf1088 | |||||||
Map_info | Map | I | Position | 24.1453 | Error | 0.021203 | |
Positive | Positive_clone | F09C3 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4572 | |||||
4793 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00001752 | ||||||
WBPaper00013425 | |||||||
WBPaper00024200 | |||||||
WBPaper00035198 | |||||||
WBPaper00038491 | |||||||
WBPaper00045213 | |||||||
WBPaper00055090 | |||||||
WBPaper00059357 | |||||||
WBPaper00061547 | |||||||
Remark | Gene name created from parsing 'genotype' field from CGC strain information [krb 020721] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |