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WormBase Tree Display for Gene: WBGene00003969

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Name Class

WBGene00003969SMapS_parentSequenceF23H11
IdentityVersion1
NameCGC_namepef-1
Sequence_nameF23H11.8
Molecular_nameF23H11.8a
F23H11.8a.1
CE27999
F23H11.8b
CE30662
F23H11.8c
CE43732
F23H11.8b.1
F23H11.8b.2
F23H11.8c.1
Other_nameCELE_F23H11.8Accession_evidenceNDBBX284603
Public_namepef-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpef
Allele (265)
StrainWBStrain00032302
WBStrain00047611
RNASeq_FPKM (74)
GO_annotation (24)
Contained_in_operonCEOP3805
Ortholog (42)
Paralog (44)
Structured_descriptionConcise_descriptionpef-1 encodes an ortholog of the rhodopsin-specific serine/threonine phosphatase RdgC in D. melanogaster and of RdgC-related proteins in humans (PPEF1 and PPEF2; OMIM:300109 and OMIM:602256); PEF-1 has a EF-hand calcium-binding domain, and is peripherally bound to the plasma membrane by myristoylation and palmitoylation; pef-1 has no known mutant phenotype, but is expressed in several anterior amphid neurons, from what appears to be the 3-fold embryo stage onward; on the basis of its expression and its orthology, PEF-1 may negatively regulate signalling through serpentine receptors such as STR-2.Paper_evidenceWBPaper00004766
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in detection of stimulus involved in sensory perception. Located in neuronal cell body. Expressed in hypodermis; intestinal cell; muscle cell; and neurons. Is an ortholog of human PPEF1 (protein phosphatase with EF-hand domain 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF23H11.8a
F23H11.8b
F23H11.8c
Corresponding_transcriptF23H11.8a.1
F23H11.8b.1
F23H11.8b.2
F23H11.8c.1
Other_sequence (26)
Associated_featureWBsf666552
WBsf991188
WBsf226159
WBsf226160
WBsf226161
Experimental_infoRNAi_resultWBRNAi00045447Inferred_automaticallyRNAi_primary
WBRNAi00006514Inferred_automaticallyRNAi_primary
WBRNAi00115957Inferred_automaticallyRNAi_primary
WBRNAi00013834Inferred_automaticallyRNAi_primary
Expr_patternExpr1500
Expr2115
Expr1020293
Expr1031893
Expr1149366
Expr2014817
Expr2033051
Drives_constructWBCnstr00010314
WBCnstr00035766
Construct_productWBCnstr00035766
AntibodyWBAntibody00000387
Microarray_results (25)
Expression_cluster (146)
Interaction (17)
Map_infoMapIIIPosition-25.0941Error0.017637
PositivePositive_cloneF23H11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5654
Pseudo_map_position
ReferenceWBPaper00004766
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene