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WormBase Tree Display for Gene: WBGene00003960

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Name Class

WBGene00003960SMapS_parentSequenceF54D5
IdentityVersion1
NameCGC_namepcs-1Person_evidenceWBPerson819
Sequence_nameF54D5.1
Molecular_nameF54D5.1a
F54D5.1a.1
CE40964
F54D5.1b
CE40965
F54D5.1b.1
Other_nameTFIIE-betaAccession_evidenceEMBLY08815
CePCSPaper_evidenceWBPaper00037940
CELE_F54D5.1Accession_evidenceNDBBX284602
Public_namepcs-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpcs
Allele (47)
StrainWBStrain00039997
WBStrain00040000
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (25)
Structured_descriptionConcise_descriptionpcs-1 encodes a phytochelatin synthase; PCS-1 exhibits cadmium-activated synthesis of phytochelatins, peptides with the general structure (gamma-Glu-Cys)n-Xaa that sequester heavy metals, and is required in animals for the response to, and detoxification of cadmium; when expressed in yeast, PCS-1 also mediates the detoxification of mercury and arsenic.Paper_evidenceWBPaper00004738
WBPaper00025092
Curator_confirmedWBPerson1843
Date_last_updated12 Mar 2010 00:00:00
Automated_descriptionEnables glutathione gamma-glutamylcysteinyltransferase activity. Involved in phytochelatin biosynthetic process and response to metal ion. Expressed in several structures, including coelomocyte; non-striated muscle; pharyngeal-intestinal valve; pharynx; and rectal valve cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF54D5.1a
F54D5.1b
Corresponding_CDS_historyF54D5.1:wp175
Corresponding_transcriptF54D5.1a.1
F54D5.1b.1
Other_sequence (29)
Associated_featureWBsf650596
WBsf666168
WBsf981287
WBsf223963
Experimental_infoRNAi_result (11)
Expr_patternChronogram598
Expr108
Expr3101
Expr9005
Expr1025837
Expr1031884
Expr1152108
Expr2014789
Expr2033023
Drives_constructWBCnstr00002739
WBCnstr00007021
WBCnstr00011137
WBCnstr00035773
Construct_productWBCnstr00035773
Microarray_results (20)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:bodywall-muscle_larva_enriched
WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:germline-precursors_embryo_enriched
WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
WBPaper00042194:nhr-114(RNAi)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044760:germline_specific
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_upregulated
WBPaper00046012:tdp-1(ok803)_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050990:intestine_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:body-wall-muscle_specific
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053321:PGCs_enriched_NuGen
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053810:clk-1(qm30)_upregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00053810:sod-2(ok1030)_upregulated
WBPaper00055941:atfs-1(et15)_upregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
WBPaper00059537:ngn-1(ok2200)_upregulated
WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
WBPaper00059987:Wounding_upregulated
WBPaper00060084:cco-1(RNAi)_upregulated_N2
WBPaper00060278:atp-2(RNAi)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060909:atfs-1(et18)_upregulated
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061527:lst-4_22151-F46F11.6_12556
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062456:doxycycline_upregulated_CB4856_protein
WBPaper00063930:BRD-1_interacting
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064716:paraquat_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00065373:sek-1(km4)_upregulated_cisplatin
WBPaper00065841:30_4
WBPaper00065841:41_0
WBPaper00065841:41_1
WBPaper00065841:78_0
WBPaper00065975:P-body_vs_WholeAnimal_enriched
cgc4489_group_1
WBPaper00025032:cluster_4
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026952:class_B
WBPaper00026980:intestine_enriched
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032948:FedUp
WBPaper00034757:up_by_oxidative_stress
WBPaper00035905:FBF-1_Associated
WBPaper00036286:Pattern_B
WBPaper00036429:glp-1(oz112)_upregulated
WBPaper00038231:Cry5B_1.5-fold_upregulated
WBPaper00038231:Cry5B_2-fold_upregulated
WBPaper00040426:CYD-1_CDK-4_downregulated
WBPaper00040963:TA300_down
WBPaper00041370:spg-7(RNAi)_upregulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045263:ProLongevity-mtROS_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
[cgc5767]:cluster_9
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:Cluster_F
[cgc6390]:intrinsic
InteractionWBInteraction000313166
WBInteraction000524519
WBInteraction000566350
WBInteraction000566629
WBInteraction000576338
WBProcessWBbiopr:00000065
WBbiopr:00000096
Map_infoMapIIPosition3.768Error0.004725
PositivePositive_cloneF54D5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point5063
5479
Pseudo_map_position
Reference (17)
RemarkSequence connection from [Vatamaniuk OK, Bucher EA]. krb 13/11/01
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene