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WormBase Tree Display for Gene: WBGene00003953

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Name Class

WBGene00003953EvidenceCGC_data_submission
SMapS_parentSequenceF39H11
IdentityVersion1
NameCGC_namepbs-7Person_evidenceWBPerson1551
Sequence_nameF39H11.5
Molecular_nameF39H11.5
F39H11.5.1
CE20761
Other_nameCELE_F39H11.5Accession_evidenceNDBBX284601
Public_namepbs-7
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpbs
Allele (14)
StrainWBStrain00051314
WBStrain00051922
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (36)
Paralog (13)
Structured_descriptionConcise_descriptionpbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development.Paper_evidenceWBPaper00004402
WBPaper00004540
WBPaper00006395
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB4 (proteasome 20S subunit beta 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060916Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9541)
Molecular_infoCorresponding_CDSF39H11.5
Corresponding_transcriptF39H11.5.1
Other_sequence (64)
Associated_featureWBsf649408
WBsf219963
WBsf219964
Experimental_infoRNAi_result (29)
Expr_patternExpr1022520
Expr1031879
Expr1150672
Expr2014771
Expr2033005
Drives_constructWBCnstr00035779
Construct_productWBCnstr00035779
Microarray_results (21)
Expression_cluster (147)
Interaction (156)
Map_infoMapIPosition3.01831Error0.00013
PositivePositive_cloneF39H11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene