WormBase Tree Display for Gene: WBGene00003953

WBGene00003953 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F39H11
  Identity: Version: 1
    Name: CGC_name: pbs-7 Person_evidence: WBPerson1551
      Sequence_name: F39H11.5
      Molecular_name: F39H11.5
        F39H11.5.1
        CE20761
      Other_name: CELE_F39H11.5 Accession_evidence: NDB BX284601
      Public_name: pbs-7
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pbs
    Allele (14)
    Strain: WBStrain00051314
      WBStrain00051922
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (36)
    Paralog (13)
    Structured_description: Concise_description: pbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development. Paper_evidence: WBPaper00004402
            WBPaper00004540
            WBPaper00006395
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB4 (proteasome 20S subunit beta 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060916 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9541)
  Molecular_info: Corresponding_CDS: F39H11.5
    Corresponding_transcript: F39H11.5.1
    Other_sequence (64)
    Associated_feature: WBsf649408
      WBsf219963
      WBsf219964
  Experimental_info: RNAi_result (29)
    Expr_pattern: Expr1022520
      Expr1031879
      Expr1150672
      Expr2014771
      Expr2033005
    Drives_construct: WBCnstr00035779
    Construct_product: WBCnstr00035779
    Microarray_results (21)
    Expression_cluster (147)
    Interaction: WBInteraction000028518
      WBInteraction000035082
      WBInteraction000036208
      WBInteraction000037007
      WBInteraction000037013
      WBInteraction000038499
      WBInteraction000039761
      WBInteraction000040343
      WBInteraction000040347
      WBInteraction000040751
      WBInteraction000040763
      WBInteraction000040773
      WBInteraction000040782
      WBInteraction000040783
      WBInteraction000040784
      WBInteraction000040785
      WBInteraction000040786
      WBInteraction000040787
      WBInteraction000040788
      WBInteraction000040789
      WBInteraction000040790
      WBInteraction000040857
      WBInteraction000042471
      WBInteraction000043618
      WBInteraction000043847
      WBInteraction000047386
      WBInteraction000047418
      WBInteraction000047866
      WBInteraction000048749
      WBInteraction000048762
      WBInteraction000048777
      WBInteraction000048784
      WBInteraction000049200
      WBInteraction000049527
      WBInteraction000050788
      WBInteraction000050823
      WBInteraction000102229
      WBInteraction000102453
      WBInteraction000102610
      WBInteraction000102679
      WBInteraction000102689
      WBInteraction000102838
      WBInteraction000102931
      WBInteraction000103100
      WBInteraction000104874
      WBInteraction000108879
      WBInteraction000109368
      WBInteraction000109751
      WBInteraction000109756
      WBInteraction000111527
      WBInteraction000111528
      WBInteraction000111529
      WBInteraction000111530
      WBInteraction000111531
      WBInteraction000111532
      WBInteraction000111533
      WBInteraction000111534
      WBInteraction000111535
      WBInteraction000111536
      WBInteraction000111551
      WBInteraction000111564
      WBInteraction000111574
      WBInteraction000111609
      WBInteraction000111627
      WBInteraction000111635
      WBInteraction000111645
      WBInteraction000111654
      WBInteraction000111736
      WBInteraction000125698
      WBInteraction000125705
      WBInteraction000141522
      WBInteraction000141789
      WBInteraction000150271
      WBInteraction000154316
      WBInteraction000154317
      WBInteraction000154318
      WBInteraction000154319
      WBInteraction000183407
      WBInteraction000185443
      WBInteraction000185476
      WBInteraction000194908
      WBInteraction000195942
      WBInteraction000198606
      WBInteraction000204183
      WBInteraction000209773
      WBInteraction000209774
      WBInteraction000218050
      WBInteraction000218051
      WBInteraction000218052
      WBInteraction000218053
      WBInteraction000219525
      WBInteraction000222536
      WBInteraction000225286
      WBInteraction000227953
      WBInteraction000231904
      WBInteraction000249689
      WBInteraction000258568
      WBInteraction000261097
      WBInteraction000265336
      WBInteraction000276945
      WBInteraction000297177
      WBInteraction000311886
      WBInteraction000334160
      WBInteraction000343502
      WBInteraction000351195
      WBInteraction000359451
      WBInteraction000360629
      WBInteraction000368637
      WBInteraction000373143
      WBInteraction000373989
      WBInteraction000386305
      WBInteraction000390843
      WBInteraction000395397
      WBInteraction000399894
      WBInteraction000422593
      WBInteraction000426649
      WBInteraction000432860
      WBInteraction000442851
      WBInteraction000442852
      WBInteraction000444553
      WBInteraction000446564
      WBInteraction000457401
      WBInteraction000460634
      WBInteraction000467996
      WBInteraction000468208
      WBInteraction000468696
      WBInteraction000469437
      WBInteraction000469987
      WBInteraction000473855
      WBInteraction000473856
      WBInteraction000474168
      WBInteraction000474689
      WBInteraction000520328
      WBInteraction000523369
      WBInteraction000523370
      WBInteraction000523371
      WBInteraction000523372
      WBInteraction000542089
      WBInteraction000542548
      WBInteraction000551090
      WBInteraction000551091
      WBInteraction000551092
      WBInteraction000551093
      WBInteraction000551094
      WBInteraction000551095
      WBInteraction000551907
      WBInteraction000560477
      WBInteraction000560478
      WBInteraction000560479
      WBInteraction000560480
      WBInteraction000560481
      WBInteraction000564129
      WBInteraction000573499
      WBInteraction000577670
      WBInteraction000580230
      WBInteraction000582525
  Map_info: Map: I Position: 3.01831 Error: 0.00013
    Positive: Positive_clone: F39H11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene