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WormBase Tree Display for Gene: WBGene00003953

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Name Class

WBGene00003953EvidenceCGC_data_submission
SMapS_parentSequenceF39H11
IdentityVersion1
NameCGC_namepbs-7Person_evidenceWBPerson1551
Sequence_nameF39H11.5
Molecular_nameF39H11.5
F39H11.5.1
CE20761
Other_nameCELE_F39H11.5Accession_evidenceNDBBX284601
Public_namepbs-7
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpbs
Allele (14)
StrainWBStrain00051314
WBStrain00051922
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (36)
Paralog (13)
Structured_descriptionConcise_descriptionpbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development.Paper_evidenceWBPaper00004402
WBPaper00004540
WBPaper00006395
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB4 (proteasome 20S subunit beta 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060916Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9541)
Molecular_infoCorresponding_CDSF39H11.5
Corresponding_transcriptF39H11.5.1
Other_sequence (64)
Associated_featureWBsf649408
WBsf219963
WBsf219964
Experimental_infoRNAi_result (29)
Expr_patternExpr1022520
Expr1031879
Expr1150672
Expr2014771
Expr2033005
Drives_constructWBCnstr00035779
Construct_productWBCnstr00035779
Microarray_results (21)
Expression_cluster (147)
Interaction (156)
Map_infoMapIPosition3.01831Error0.00013
PositivePositive_cloneF39H11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00024430
WBPaper00029221
WBPaper00030965
WBPaper00032236
WBPaper00035228
WBPaper00036083
WBPaper00038491
WBPaper00055090
WBPaper00056008
WBPaper00060474
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene