WormBase Tree Display for Gene: WBGene00003847
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| WBGene00003847 | SMap | S_parent | Sequence | F25D7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | blmp-1 | Paper_evidence | WBPaper00045431 | |||||
| Person_evidence | WBPerson3099 | ||||||||
| Sequence_name | F25D7.3 | ||||||||
| Molecular_name | F25D7.3a | ||||||||
| F25D7.3a.1 | |||||||||
| CE09631 | |||||||||
| F25D7.3b | |||||||||
| CE43409 | |||||||||
| F25D7.3b.1 | |||||||||
| Other_name | odd-3 | CGC_data_submission | |||||||
| dpy-24 | Person_evidence | WBPerson261 | |||||||
| CELE_F25D7.3 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | blmp-1 | ||||||||
| DB_info | Database | AceView | gene | 1K989 | |||||
| WormQTL | gene | WBGene00003847 | |||||||
| WormFlux | gene | WBGene00003847 | |||||||
| NDB | locus_tag | CELE_F25D7.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003847|UniProtKB=Q93560 | |||||||
| family | PTHR16515 | ||||||||
| NCBI | gene | 172917 | |||||||
| RefSeq | protein | NM_001264442.2 | |||||||
| NM_001264441.2 | |||||||||
| SwissProt | UniProtAcc | Q93560 | |||||||
| TREEFAM | TREEFAM_ID | TF316545 | |||||||
| UniProt_GCRP | UniProtAcc | Q93560 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 18 May 2005 13:24:17 | WBPerson2970 | Name_change | CGC_name | blmp-1 | ||||
| Other_name | odd-3 | ||||||||
| 3 | 14 Aug 2014 11:02:14 | WBPerson2970 | Event | Acquires_merge | WBGene00001083 | ||||
| Name_change | Other_name | dpy-24 | |||||||
| Acquires_merge | WBGene00001083 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | blmp | ||||||||
| Allele (68) | |||||||||
| Legacy_information | s71 : weak dumpy. ES3 (adult) ES1 (larvae). NA1. | ||||||||
| [C.elegansII] s71 : weak dumpy; abnormal DTC migration. ES3 (adult) ES1 (larvae). NA1. [Hedgecock et al. 1987; BC; BS] | |||||||||
| Strain | WBStrain00022557 | ||||||||
| WBStrain00034109 | |||||||||
| WBStrain00034369 | |||||||||
| WBStrain00000464 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (26) | |||||||||
| Ortholog (37) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | blmp-1 encodes a zinc finger and SET domain-containing protein that is the C. elegans BLIMP1 (B lymphocyte-induced maturation protein 1) ortholog; loss of blmp-1 activity via deletion mutation has been reported to result in small, dumpy animals with abnormal fat content, while loss of blmp-1 activity via RNAi reportedly results in animals that are small, dumpy, have an amorphous pharynx, and are uncoordinated with patchy coloration and protruding vulvae; a blmp-1::gfp transcriptional fusion is expressed from late embryogenesis through adulthood and found in a variety of tissues including hypodermis, seam cells, gonad distal tip cells and vulva, ventral nerve cord, amphids and phasmids, and rectal muscles. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00006395 | |||||||||
| WBPaper00029055 | |||||||||
| WBPaper00030864 | |||||||||
| WBPaper00040399 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 16 Nov 2011 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of distal tip cell migration; regulation of developmental process; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in several structures, including distal tip cell; dorsal nerve cord; enteric muscle; neurons; and tail hypodermis. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and non-Hodgkin lymphoma (multiple). Is an ortholog of human PRDM1 (PR/SET domain 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080797 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9346) | ||||
| DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9346) | ||||||
| DOID:0050745 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9346) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9346) | ||||||
| DOID:1324 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9346) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9346) | ||||||
| Molecular_info | Corresponding_CDS | F25D7.3a | |||||||
| F25D7.3b | |||||||||
| Corresponding_transcript | F25D7.3a.1 | ||||||||
| F25D7.3b.1 | |||||||||
| Other_sequence (27) | |||||||||
| Associated_feature (13) | |||||||||
| Gene_product_binds (10744) | |||||||||
| Transcription_factor | WBTranscriptionFactor000004 | ||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern (15) | |||||||||
| Drives_construct | WBCnstr00007730 | ||||||||
| WBCnstr00008157 | |||||||||
| WBCnstr00012664 | |||||||||
| WBCnstr00019673 | |||||||||
| WBCnstr00023092 | |||||||||
| WBCnstr00035833 | |||||||||
| WBCnstr00042568 | |||||||||
| WBCnstr00042569 | |||||||||
| Construct_product | WBCnstr00007730 | ||||||||
| WBCnstr00008157 | |||||||||
| WBCnstr00023092 | |||||||||
| WBCnstr00035833 | |||||||||
| WBCnstr00042569 | |||||||||
| Regulate_expr_cluster | WBPaper00045017:blmp-1(tm548)_downregulated | ||||||||
| WBPaper00045017:blmp-1(tm548)_upregulated | |||||||||
| WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_downregulated | |||||||||
| WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_upregulated | |||||||||
| WBPaper00049732:blmp-1(tm548)_vs_N2_downregulated | |||||||||
| WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated | |||||||||
| WBPaper00062347:blmp-1(tm548)_downregulated | |||||||||
| WBPaper00062347:blmp-1(tm548)_upregulated | |||||||||
| WBPaper00062715:blmp-1(s71)_downregulated | |||||||||
| WBPaper00062715:blmp-1(s71)_upregulated | |||||||||
| Antibody | WBAntibody00002520 | ||||||||
| WBAntibody00002528 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (181) | |||||||||
| Interaction (70) | |||||||||
| Product_binds_matrix | WBPmat00005558 | ||||||||
| Map_info | Map | I | Position | 4.9856 | Error | 0.009659 | |||
| Positive | Positive_clone | F25D7 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | 2_point | 464 | |||||||
| 5839 | |||||||||
| 6047 | |||||||||
| 6048 | |||||||||
| 6214 | |||||||||
| Multi_point (24) | |||||||||
| Pos_neg_data | 2512 | ||||||||
| 5841 | |||||||||
| 5843 | |||||||||
| 5845 | |||||||||
| 5847 | |||||||||
| 8063 | |||||||||
| 8074 | |||||||||
| 8085 | |||||||||
| 8131 | |||||||||
| 8136 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (65) | |||||||||
| Remark | Sequence connection from [Strohmaier K, Rothman JH] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
