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WormBase Tree Display for Gene: WBGene00003796

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Name Class

WBGene00003796SMapS_parentSequenceZK328
IdentityVersion1
NameCGC_namenpp-10Person_evidenceWBPerson1780
Sequence_nameZK328.5
Molecular_nameZK328.5a
ZK328.5a.1
CE44281
ZK328.5b
CE44292
ZK328.5c
CE44327
ZK328.5b.1
ZK328.5c.1
Other_nameNup96Paper_evidenceWBPaper00026834
Nup98Paper_evidenceWBPaper00026834
CELE_ZK328.5Accession_evidenceNDBBX284603
Public_namenpp-10
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnpp
Allele (84)
Possibly_affected_byWBVar02154080
StrainWBStrain00035673
WBStrain00022364
WBStrain00055401
WBStrain00054175
RNASeq_FPKM (74)
GO_annotation (51)
Ortholog (43)
Structured_descriptionConcise_descriptionnpp-10 is orthologous to the human gene NUCLEOPORIN, 98-KD (NUP98; OMIM:601021), which can promote leukemias (myelodysplastic syndromes, AML, or CML) when chromosomally rearranged.Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables RNA binding activity. Involved in embryo development; organelle organization; and protein localization to organelle. Located in P granule; kinetochore; and nuclear envelope. Part of nuclear pore. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Is an ortholog of human NUP98 (nucleoporin 98 and 96 precursor).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5603Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8068)
Molecular_infoCorresponding_CDSZK328.5a
ZK328.5b
ZK328.5c
Corresponding_CDS_historyZK328.5a:wp101
ZK328.5a:wp209
ZK328.5b:wp101
ZK328.5b:wp209
Corresponding_transcriptZK328.5a.1
ZK328.5b.1
ZK328.5c.1
Other_sequence (19)
Associated_featureWBsf655439
WBsf666428
WBsf666948
WBsf666949
WBsf226748
WBsf226749
WBsf226750
WBsf226751
Experimental_infoRNAi_result (21)
Expr_patternExpr9020
Expr9024
Expr1026045
Expr1031782
Expr1162768
Expr2014370
Expr2032611
Drives_constructWBCnstr00035863
WBCnstr00042404
Construct_productWBCnstr00006025
WBCnstr00013677
WBCnstr00035863
WBCnstr00042404
AntibodyWBAntibody00001025
WBAntibody00001887
WBAntibody00001888
WBAntibody00001893
WBAntibody00002138
WBAntibody00002139
Microarray_results (32)
Expression_cluster (141)
Interaction (183)
Map_infoMapIIIPosition-1.42704Error0.000206
PositivePositive_cloneZK328Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4248
4546
Pseudo_map_position
Reference (19)
RemarkSequence connection from [Askjaer P, Mattaj IW]. krb 13/11/01
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene