WormBase Tree Display for Gene: WBGene00003539

WBGene00003539 Evidence: Author_evidence: Moehrlen F
  SMap: S_parent: Sequence: T11F9
  Identity: Version: 1
    Name: CGC_name: nas-20 Person_evidence: WBPerson1103
      Sequence_name: T11F9.3
      Molecular_name: T11F9.3
        T11F9.3.1
        CE35907
      Other_name: CELE_T11F9.3 Accession_evidence: NDB BX284605
      Public_name: nas-20
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nas
    Allele (21)
    Strain: WBStrain00033239
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (30)
    Paralog (48)
    Structured_description: Concise_description: nas-20 encodes an astacin-like metalloprotease. Paper_evidence: WBPaper00006254
          Curator_confirmed: WBPerson1843
          Date_last_updated: 15 Feb 2008 00:00:00
      Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T11F9.3
    Corresponding_CDS_history: T11F9.3:wp111
    Corresponding_transcript: T11F9.3.1
    Other_sequence: JI219344.1
    Associated_feature: WBsf234539
  Experimental_info: RNAi_result: WBRNAi00053126 Inferred_automatically: RNAi_primary
      WBRNAi00018603 Inferred_automatically: RNAi_primary
      WBRNAi00035479 Inferred_automatically: RNAi_primary
      WBRNAi00089156 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022996
      Expr1156732
      Expr2013870
      Expr2032109
    Drives_construct: WBCnstr00036058
    Construct_product: WBCnstr00036058
    Microarray_results (21)
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00036738:4uM_Heme_upregulated
      WBPaper00037682:sma-2_sma-4_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00041954:ethanol_upregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_upregulated_transcript
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045971:tunicamycin_upregulated_RtcB(null)
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048926:miaserin_upregulated_adult-day3
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048926:miaserin_upregulated_adult-day10
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049736:15deg-then-25deg(12hr)_downregulated_N2
      WBPaper00049905:Age_variant_expression
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053782:daf-2(RNAi)_oocyte_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00054410:set-9(rw5)_downregulated
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:Allantoin_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Metformin_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055648:male-vas-deferens_expressed
      WBPaper00055648:vulva-uterus_expressed
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00055981:fog-2(q71)_upregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056290:mdt-15(mg584)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057265:metaformin_upregulated_OP50
      WBPaper00058948:PA14_upregulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060911:prx-5(RNAi)_downregulated_mRNA
      WBPaper00061040:eat-2(ad1116)_downregulated
      WBPaper00061081:E.faecalis_downregulated_N2
      WBPaper00061106:endu-2(tm4977)_upregulated
      WBPaper00061340:AVG
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:ZC373.2-Y62H9A.6_1596
      WBPaper00061651:PVR_enriched
      WBPaper00062103:neuron_enriched
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062456:doxycycline_downregulated_N2_protein
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064130:Beta-Amyloid_downregulated_protein
      WBPaper00064494:postdauer_downregulated_WholeAnimal
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064661:lpd-3(ok2138)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064841:tent-5(tm3504)_downregulated_transcript
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064952:Day10_vs_Day1_upregulated_20C
      WBPaper00064952:Day10_vs_Day5_upregulated_20C
      WBPaper00064952:Day10_vs_L4_upregulated_20C
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_25C
      WBPaper00065158:25C_vs_15C_downregulated_AFD
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00065623:68
      WBPaper00065749:endu-2(tm4977)_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:11_3
      WBPaper00065841:137_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      cgc4386_cluster_4_2
      cgc4489_group_12
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_B
      WBPaper00029437:rde-4_upregulated
      WBPaper00031703:heme_responsive_2
      WBPaper00034661:AgNPs_upregulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037695:CC_3-day
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040184:hcf-1down_sir-2.1nc_daf-2nc
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:Q50_up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041609:hpl-1_hpl-2_downregulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00042574:rde-1(ne219)_OrsayVirus_downregulated
      WBPaper00044535:male_downregulated
      WBPaper00045015:nhr-25(RNAi)_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00051387:Triclosan_downregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:mixed_oogenesis-somatic
    Interaction (155)
  Map_info: Map: V Position: 3.13921 Error: 0.004557
    Positive: Positive_clone: T11F9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006254
    WBPaper00032165
    WBPaper00055090
    WBPaper00063976
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene