WormBase Tree Display for Gene: WBGene00003523
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| WBGene00003523 | Evidence | Author_evidence | Moehrlen F | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C05D11 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | nas-4 | Person_evidence | WBPerson1103 | |||||
| Sequence_name | C05D11.6 | ||||||||
| Molecular_name | C05D11.6a | ||||||||
| C05D11.6a.1 | |||||||||
| CE37080 | |||||||||
| C05D11.6b | |||||||||
| CE44904 | |||||||||
| C05D11.6c | |||||||||
| CE44965 | |||||||||
| C05D11.6a.2 | |||||||||
| C05D11.6b.1 | |||||||||
| C05D11.6c.1 | |||||||||
| Other_name | CELE_C05D11.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | nas-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nas | ||||||||
| Allele (55) | |||||||||
| Strain | WBStrain00035277 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (28) | |||||||||
| Paralog (48) | |||||||||
| Structured_description | Concise_description | nas-4 encodes a predicted extracellular matrix metalloprotease of the M12A (astacin) family that contains an N-terminal signal sequence and a catalytic domain, but no recognizable regulatory domains in the C-terminus; as loss of nas-4 activity via RNAi results in no obvious abnormalities, the precise role of NAS-4 in C. elegans development and/or behavior is not yet known; however, an NAS-4 translational reporter is expressed in the pharynx and intestine in larvae and adults, suggesting a role for NAS-4 in digestion; NAS-4 is specifically detected within cells of the pharyngeal procorpus, metacorpus, isthmus, and terminal bulb, with extracellular expression detected in the lumen of the terminal bulb and in the gut. | Paper_evidence | WBPaper00004403 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00006254 | |||||||||
| WBPaper00024497 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 15 Nov 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in intestine; marginal cell; and pharynx. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C05D11.6a | |||||||
| C05D11.6b | |||||||||
| C05D11.6c | |||||||||
| Corresponding_CDS_history | C05D11.6:wp112 | ||||||||
| C05D11.6:wp127 | |||||||||
| Corresponding_transcript | C05D11.6a.1 | ||||||||
| C05D11.6a.2 | |||||||||
| C05D11.6b.1 | |||||||||
| C05D11.6c.1 | |||||||||
| Other_sequence | FC547268.1 | ||||||||
| JO469184.1 | |||||||||
| ACC23389_1 | |||||||||
| JI181768.1 | |||||||||
| CJC16588_1 | |||||||||
| Dviv_isotig26663 | |||||||||
| Associated_feature | WBsf992756 | ||||||||
| WBsf226811 | |||||||||
| WBsf226812 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00028497 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00039738 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005475 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039739 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00088977 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022273 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005306 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram170 | ||||||||
| Expr2803 | |||||||||
| Expr7412 | |||||||||
| Expr8907 | |||||||||
| Expr1025181 | |||||||||
| Expr1143830 | |||||||||
| Expr2013887 | |||||||||
| Expr2032127 | |||||||||
| Drives_construct | WBCnstr00001207 | ||||||||
| WBCnstr00010956 | |||||||||
| WBCnstr00012555 | |||||||||
| WBCnstr00013601 | |||||||||
| WBCnstr00036072 | |||||||||
| Construct_product | WBCnstr00010956 | ||||||||
| WBCnstr00013601 | |||||||||
| WBCnstr00036072 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (164) | |||||||||
| Interaction (44) | |||||||||
| Map_info | Map | III | Position | -1.28376 | Error | 0.000983 | |||
| Positive | Positive_clone | C05D11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00006254 | ||||||||
| WBPaper00025850 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00058138 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
