WormBase Tree Display for Gene: WBGene00003517

WBGene00003517 Evidence: Paper_evidence: WBPaper00005726
  SMap: S_parent: Sequence: F31F6
  Identity: Version: 1
    Name: CGC_name: nac-1
      Sequence_name: F31F6.6
      Molecular_name: F31F6.6
        F31F6.6.1
        CE34007
      Other_name: indy-1 Accession_evidence: EMBL AY090484
        nad-1
        cenadc1
        CELE_F31F6.6 Accession_evidence: NDB BX284606
      Public_name: nac-1
    DB_info: Database: AceView gene XP515
        WormQTL gene WBGene00003517
        WormFlux gene WBGene00003517
        NDB locus_tag CELE_F31F6.6
        Panther gene CAEEL|WormBase=WBGene00003517|UniProtKB=Q93655
          family PTHR10283
        NCBI gene 181585
        RefSeq protein NM_078072.6
        SwissProt UniProtAcc Q93655
        UniProt_GCRP UniProtAcc Q93655
        OMIM gene 608305
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nac
    Allele (60)
    Strain: WBStrain00031456
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (55)
    Paralog: WBGene00003519 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00007138 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00003518 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: nac-1 encodes a low-affinity sodium-coupled dicarboxylate transporter homologous to INDY in D. melanogaster and to mammalian NaDC1 and NaDC3; nac-1 is expressed in the intestine, in larvae and adults. Paper_evidence: WBPaper00005654
            WBPaper00005726
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 10 Feb 2015 00:00:00
      Automated_description: Enables low-affinity sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in succinate transport. Predicted to be located in membrane. Expressed in alimentary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2) and SLC13A5 (solute carrier family 13 member 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080453 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23089)
  Molecular_info: Corresponding_CDS: F31F6.6
    Corresponding_CDS_history: F31F6.6:wp101
    Corresponding_transcript: F31F6.6.1
    Other_sequence: AY090484
      Hbac_isotig07691
      ACC03517_1
      Dviv_isotig26777
      Oden_isotig19715
      JI169837.1
    Associated_feature: WBsf663605
      WBsf236736
      WBsf236737
      WBsf236738
  Experimental_info: RNAi_result: WBRNAi00031637 Inferred_automatically: RNAi_primary
      WBRNAi00022870 Inferred_automatically: RNAi_primary
      WBRNAi00046061 Inferred_automatically: RNAi_primary
      WBRNAi00014182 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2367
      Expr2368
      Expr1011702
      Expr1031611
      Expr1149952
      Expr2013852
      Expr2032092
    Drives_construct: WBCnstr00010791
      WBCnstr00036077
    Construct_product: WBCnstr00036077
    Microarray_results (19)
    Expression_cluster (162)
    Interaction: WBInteraction000135776
      WBInteraction000137323
      WBInteraction000137648
      WBInteraction000144563
      WBInteraction000149042
      WBInteraction000149711
      WBInteraction000164963
      WBInteraction000176518
      WBInteraction000178402
      WBInteraction000178403
      WBInteraction000180691
      WBInteraction000182432
      WBInteraction000186153
      WBInteraction000189547
      WBInteraction000191056
      WBInteraction000196870
      WBInteraction000197052
      WBInteraction000207187
      WBInteraction000211159
      WBInteraction000212678
      WBInteraction000223236
      WBInteraction000224808
      WBInteraction000228466
      WBInteraction000231114
      WBInteraction000234601
      WBInteraction000237164
      WBInteraction000243122
      WBInteraction000249981
      WBInteraction000250693
      WBInteraction000251220
      WBInteraction000258730
      WBInteraction000260282
      WBInteraction000268855
      WBInteraction000270929
      WBInteraction000271987
      WBInteraction000275850
      WBInteraction000279337
      WBInteraction000281244
      WBInteraction000284002
      WBInteraction000285570
      WBInteraction000286523
      WBInteraction000291965
      WBInteraction000295557
      WBInteraction000295559
      WBInteraction000296484
      WBInteraction000305053
      WBInteraction000306849
      WBInteraction000312640
      WBInteraction000316432
      WBInteraction000316446
      WBInteraction000325006
      WBInteraction000325772
      WBInteraction000327170
      WBInteraction000328178
      WBInteraction000331970
      WBInteraction000335325
      WBInteraction000343185
      WBInteraction000343303
      WBInteraction000346010
      WBInteraction000347057
      WBInteraction000351525
      WBInteraction000355002
      WBInteraction000368920
      WBInteraction000371289
      WBInteraction000389964
      WBInteraction000394603
      WBInteraction000410965
      WBInteraction000413005
      WBInteraction000414940
      WBInteraction000416422
      WBInteraction000425618
      WBInteraction000426603
      WBInteraction000433872
      WBInteraction000441583
      WBInteraction000442666
      WBInteraction000449569
      WBInteraction000455233
      WBInteraction000460225
      WBInteraction000462058
      WBInteraction000463257
      WBInteraction000463503
      WBInteraction000463746
      WBInteraction000463877
      WBInteraction000464225
      WBInteraction000465970
      WBInteraction000466186
      WBInteraction000466430
      WBInteraction000466572
      WBInteraction000466615
      WBInteraction000466796
      WBInteraction000467021
      WBInteraction000467161
      WBInteraction000467163
      WBInteraction000467240
      WBInteraction000467309
      WBInteraction000467461
      WBInteraction000468627
      WBInteraction000468774
      WBInteraction000468901
      WBInteraction000469158
      WBInteraction000469935
      WBInteraction000471052
      WBInteraction000471108
      WBInteraction000471215
      WBInteraction000471665
      WBInteraction000471811
      WBInteraction000472479
      WBInteraction000473763
      WBInteraction000473808
      WBInteraction000474493
      WBInteraction000474582
      WBInteraction000474671
      WBInteraction000475176
      WBInteraction000475414
  Map_info: Map: X Position: 21.5469 Error: 0.012103
    Positive: Positive_clone: F31F6 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4508
    Pseudo_map_position
  Reference: WBPaper00005726
    WBPaper00006504
    WBPaper00025195
    WBPaper00031333
    WBPaper00035539
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene