WormBase Tree Display for Gene: WBGene00003495
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| WBGene00003495 | SMap | S_parent | Sequence | T22E5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mup-2 | Person_evidence | WBPerson1052 | |||||
| Sequence_name | T22E5.5 | ||||||||
| Molecular_name | T22E5.5 | ||||||||
| T22E5.5.1 | |||||||||
| CE04994 | |||||||||
| Other_name | tnt-1 | ||||||||
| CELE_T22E5.5 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | mup-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mup | ||||||||
| Allele (28) | |||||||||
| Legacy_information | [C.elegansII] e2346ts : embryonic temp-shift leads to lethal mispositioning and deformity of body-wall muscle; larval temp-shift leads to sterility, defects in oviduct muscle. OA1: up1 (non-conditional, lethal with arrest as kinked larva; probable null, nonsense mutation). Cloned: encodes troponin T homolog. [EE; UG] | ||||||||
| Strain | WBStrain00006650 | ||||||||
| WBStrain00006651 | |||||||||
| WBStrain00006652 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00006587 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00006589 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00006588 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility. | Paper_evidence | WBPaper00002414 | |||||
| WBPaper00003294 | |||||||||
| WBPaper00006395 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 11 Mar 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable tropomyosin binding activity. Involved in several processes, including axonal fasciculation; muscle structure development; and ovulation. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including distal arthrogryposis type 2B2; intrinsic cardiomyopathy (multiple); and nemaline myopathy (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (14) | ||||||||
| Molecular_info | Corresponding_CDS | T22E5.5 | |||||||
| Corresponding_transcript | T22E5.5.1 | ||||||||
| Other_sequence (140) | |||||||||
| Associated_feature | WBsf654064 | ||||||||
| WBsf670625 | |||||||||
| WBsf670626 | |||||||||
| WBsf1005570 | |||||||||
| WBsf1005571 | |||||||||
| WBsf1023097 | |||||||||
| WBsf237478 | |||||||||
| WBsf237479 | |||||||||
| WBsf237480 | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr1026876 | ||||||||
| Expr1031599 | |||||||||
| Expr1157386 | |||||||||
| Expr2013825 | |||||||||
| Expr2032065 | |||||||||
| Drives_construct | WBCnstr00036087 | ||||||||
| Construct_product | WBCnstr00036087 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (248) | |||||||||
| Interaction (72) | |||||||||
| WBProcess | WBbiopr:00000006 | ||||||||
| WBbiopr:00000067 | |||||||||
| Map_info | Map | X | Position | -2.91797 | Error | 0.002167 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | R04A4 | |||||||
| T22E5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 3386 | |||||||
| 3694 | |||||||||
| 3958 | |||||||||
| Reference (39) | |||||||||
| Method | Gene |
