WormBase Tree Display for Gene: WBGene00003088
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| WBGene00003088 | Evidence | Paper_evidence | WBPaper00006260 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C32C4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | lsy-6 | Person_evidence | WBPerson260 | |||||
| Sequence_name | C32C4.6 | ||||||||
| Molecular_name | C32C4.6 | ||||||||
| C32C4.6a | |||||||||
| C32C4.6b | |||||||||
| Other_name | Cel-Lsy-6 | Remark | MirGeneDB 2.1 import | ||||||
| CELE_C32C4.6 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | lsy-6 | ||||||||
| DB_info | Database | SignaLink | mirna | cel-lsy-6 | |||||
| MirGeneDB | cel | Cel-Lsy-6 | |||||||
| NDB | locus_tag | CELE_C32C4.6 | |||||||
| NCBI | gene | 3565492 | |||||||
| RefSeq | protein | NR_002394.2 | |||||||
| RNAcentral | URSid | URS00003F8B2D | |||||||
| URS0000773725 | |||||||||
| URS0000778771 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001265 | |||||||
| Gene_class | lsy | ||||||||
| Allele (11) | |||||||||
| Strain (13) | |||||||||
| In_cluster | LSY-6 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00106192 | ||||||||
| 00106193 | |||||||||
| 00106194 | |||||||||
| Structured_description | Concise_description | lsy-6 encodes a microRNA and was the first microRNA discovered to have a role in nervous system development in vivo; lsy-6 is involved in the pathway for functional lateralization of the chemosensory ASE neuron; lsy-6 controls the asymmetrical expression of the gcy chemoreceptors, gcy-5 and gcy-7, in ASER and ASEL; genetic epistasis experiments indicate that the transcription of lsy-6 is regulated by lsy-2, a novel C2H2 zinc finger transcription factor; reporter gene fusion studies indicate that lsy-6 is expressed in one pair of tail neurons and seven head neurons including ASEL, but not in ASER. | Paper_evidence | WBPaper00006260 | |||||
| WBPaper00024291 | |||||||||
| WBPaper00027031 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 23 May 2006 00:00:00 | ||||||||
| Automated_description | Enables mRNA 3'-UTR binding activity. Involved in determination of left/right asymmetry in nervous system and miRNA-mediated post-transcriptional gene silencing. Expressed in ASEL; head neurons; and tail neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_transcript | C32C4.6 | |||||||
| C32C4.6a | |||||||||
| C32C4.6b | |||||||||
| Associated_feature | WBsf047573 | ||||||||
| WBsf047579 | |||||||||
| WBsf979125 | |||||||||
| Experimental_info | Expr_pattern | Expr2807 | |||||||
| Expr2808 | |||||||||
| Expr8410 | |||||||||
| Expr10657 | |||||||||
| Marker96 | |||||||||
| Drives_construct (22) | |||||||||
| Construct_product (18) | |||||||||
| Expression_cluster | WBPaper00051404:alg-1(gk214)_upregulated_miRNA | ||||||||
| WBPaper00051404:alg-2(ok304)_upregulated_miRNA | |||||||||
| WBPaper00051404:alg-5(ram2)_upregulated_miRNA | |||||||||
| WBPaper00051404:alg-5(tm1163)_upregulated_miRNA | |||||||||
| WBPaper00053318:Aging_downregulated_miRNA_N2 | |||||||||
| WBPaper00053318:mir-71(n4115)_upregulated_miRNA | |||||||||
| WBPaper00056868:P.aeruginosa_upregulated_smallRNA | |||||||||
| WBPaper00058673:hrpk-1(tm5522)_downregulated_miRNA_L4 | |||||||||
| Interaction (51) | |||||||||
| WBProcess | WBbiopr:00000082 | ||||||||
| Map_info | Map | V | Position | 2.658 | Error | 0.010694 | |||
| Positive | Positive_clone | C32C4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4882 | |||||||
| Pseudo_map_position | |||||||||
| Reference (74) | |||||||||
| Remark | lsy-6 was mistakenly connected to C32C4.5 | CGC_data_submission | |||||||
| Rfam accession number: MI0000801 | |||||||||
| lsy-6 is a microRNA | Paper_evidence | WBPaper00006260 | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
