WormBase Tree Display for Gene: WBGene00003088
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WBGene00003088 | Evidence | Paper_evidence | WBPaper00006260 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C32C4 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001265 | |||||
Gene_class | lsy | ||||||
Allele (11) | |||||||
Strain (13) | |||||||
In_cluster | LSY-6 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00106192 | ||||||
00106193 | |||||||
00106194 | |||||||
Structured_description | Concise_description | lsy-6 encodes a microRNA and was the first microRNA discovered to have a role in nervous system development in vivo; lsy-6 is involved in the pathway for functional lateralization of the chemosensory ASE neuron; lsy-6 controls the asymmetrical expression of the gcy chemoreceptors, gcy-5 and gcy-7, in ASER and ASEL; genetic epistasis experiments indicate that the transcription of lsy-6 is regulated by lsy-2, a novel C2H2 zinc finger transcription factor; reporter gene fusion studies indicate that lsy-6 is expressed in one pair of tail neurons and seven head neurons including ASEL, but not in ASER. | Paper_evidence | WBPaper00006260 | |||
WBPaper00024291 | |||||||
WBPaper00027031 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson324 | |||||||
Date_last_updated | 23 May 2006 00:00:00 | ||||||
Automated_description | Enables mRNA 3'-UTR binding activity. Involved in determination of left/right asymmetry in nervous system and miRNA-mediated post-transcriptional gene silencing. Expressed in ASEL; head neurons; and tail neurons. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_transcript | C32C4.6 | |||||
C32C4.6a | |||||||
C32C4.6b | |||||||
Associated_feature | WBsf047573 | ||||||
WBsf047579 | |||||||
WBsf979125 | |||||||
Experimental_info | Expr_pattern | Expr2807 | |||||
Expr2808 | |||||||
Expr8410 | |||||||
Expr10657 | |||||||
Marker96 | |||||||
Drives_construct (22) | |||||||
Construct_product (18) | |||||||
Expression_cluster | WBPaper00051404:alg-1(gk214)_upregulated_miRNA | ||||||
WBPaper00051404:alg-2(ok304)_upregulated_miRNA | |||||||
WBPaper00051404:alg-5(ram2)_upregulated_miRNA | |||||||
WBPaper00051404:alg-5(tm1163)_upregulated_miRNA | |||||||
WBPaper00053318:Aging_downregulated_miRNA_N2 | |||||||
WBPaper00053318:mir-71(n4115)_upregulated_miRNA | |||||||
WBPaper00056868:P.aeruginosa_upregulated_smallRNA | |||||||
WBPaper00058673:hrpk-1(tm5522)_downregulated_miRNA_L4 | |||||||
Interaction (51) | |||||||
WBProcess | WBbiopr:00000082 | ||||||
Map_info | Map | V | Position | 2.658 | Error | 0.010694 | |
Positive | Positive_clone | C32C4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4882 | |||||
Pseudo_map_position | |||||||
Reference (74) | |||||||
Remark | lsy-6 was mistakenly connected to C32C4.5 | CGC_data_submission | |||||
Rfam accession number: MI0000801 | |||||||
lsy-6 is a microRNA | Paper_evidence | WBPaper00006260 | |||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |