WormBase Tree Display for Gene: WBGene00003053
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| WBGene00003053 | SMap | S_parent | Sequence | C03B1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lmp-1 | Person_evidence | WBPerson959 | |||||
| Sequence_name | C03B1.12 | ||||||||
| Molecular_name | C03B1.12 | ||||||||
| C03B1.12.1 | |||||||||
| CE03912 | |||||||||
| Other_name | CELE_C03B1.12 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | lmp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lmp | ||||||||
| Allele (23) | |||||||||
| Strain | WBStrain00030579 | ||||||||
| WBStrain00033050 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00015471 | Caenorhabditis elegans | From_analysis | Panther | |||||
| Structured_description | Concise_description | lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus; LMP-1 is widely expressed in the early embryo, with later expression seen in the intestine, coelomocytes, and neurons; LMP-1 localizes to lysosomes and is recruited to phagosomes upon lysosomal fusion. | Paper_evidence | WBPaper00004254 | |||||
| WBPaper00006472 | |||||||||
| WBPaper00034674 | |||||||||
| WBPaper00035888 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 07 Jan 2011 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in establishment of protein localization to organelle. Located in cytoplasmic vesicle and lysosomal membrane. Expressed in coelomocyte; germ line; and pharynx. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Is an ortholog of human LAMP2 (lysosomal associated membrane protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050437 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6501) | ||||
| DOID:11984 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6501) | ||||||
| Molecular_info | Corresponding_CDS | C03B1.12 | |||||||
| Corresponding_transcript | C03B1.12.1 | ||||||||
| Other_sequence (52) | |||||||||
| Associated_feature | WBsf654062 | ||||||||
| WBsf655670 | |||||||||
| WBsf670621 | |||||||||
| WBsf1005561 | |||||||||
| WBsf1023091 | |||||||||
| WBsf237473 | |||||||||
| WBsf237474 | |||||||||
| WBsf237475 | |||||||||
| WBsf237476 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00090686 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00008328 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039488 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091312 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065622 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027912 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00001778 | ||||||||
| WBCnstr00006910 | |||||||||
| WBCnstr00012218 | |||||||||
| WBCnstr00036261 | |||||||||
| Construct_product (14) | |||||||||
| Antibody | WBAntibody00000297 | ||||||||
| WBAntibody00002186 | |||||||||
| WBAntibody00002423 | |||||||||
| WBAntibody00002667 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (153) | |||||||||
| Interaction (63) | |||||||||
| WBProcess | WBbiopr:00000121 | ||||||||
| Map_info | Map | X | Position | -2.92988 | Error | 0.003579 | |||
| Positive | Positive_clone | C03B1 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (36) | |||||||||
| Remark | Sequence connection from [Fire AZ, Kostich M, Fambrough DM] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
