WormBase Tree Display for Gene: WBGene00003044
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| WBGene00003044 | SMap | S_parent | Sequence | F18A1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | lir-1 | Person_evidence | WBPerson351 | |||||
| Sequence_name | F18A1.3 | ||||||||
| Molecular_name (43) | |||||||||
| Other_name | CELE_F18A1.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | lir-1 | ||||||||
| DB_info | Database | AceView | gene | 2H973 | |||||
| WormQTL | gene | WBGene00003044 | |||||||
| SignaLink | protein | WBGene00003044 | |||||||
| WormFlux | gene | WBGene00003044 | |||||||
| NDB | locus_tag | CELE_F18A1.3 | |||||||
| NCBI | gene | 174240 | |||||||
| RefSeq | protein (14) | ||||||||
| TrEMBL | UniProtAcc (14) | ||||||||
| UniProt_GCRP | UniProtAcc | G5EBR0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Apr 2017 14:46:33 | WBPerson2970 | Name_change | Other_name | moag-2 | ||||
| 3 | 11 May 2017 14:27:53 | WBPerson2970 | Name_change | Other_name | moag-2 removed (incorrect) | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lir | ||||||||
| Allele (153) | |||||||||
| Legacy_information | [C.elegansII] pk96 : Tc1 insertion, no known phenotype. Encodes predicted protein related and 5' to lin-26. [ML] | ||||||||
| [] lir-1 is located immediately upstream of lin-26. It encodes a protein with zinc-fingers homologous to those of LIN-26. lir stands for lin-26 related gene. | |||||||||
| Complementation_data | [] lir-1(mc33) complements the embryonic lethality of lin-26(mc15) | ||||||||
| Strain | WBStrain00026572 | ||||||||
| WBStrain00051951 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00010022 | ||||||||
| 00010023 | |||||||||
| 00105105 | |||||||||
| Contained_in_operon | CEOP2300 | ||||||||
| Ortholog (27) | |||||||||
| Paralog | WBGene00003012 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00003045 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003046 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010264 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013350 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018740 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018833 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00304808 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | lir-1 encodes a LIN-26-like zinc-finger protein that shares a unique C2H2 motif together with LIR-2, LIR-3, and LIN-26; lir-1 is part of two distinct operons: it is the downstream gene in an operon with lir-2 and the upstream gene in a second, overlapping operon with lin-26; the precise role of lir-1 in C. elegans development and/or behavior is not yet known as neither loss nor gain of lir-1 function appears to result in clear abnormalities and RNAi experiments targeting lir-1 result in embryonic and larval lethality due to loss of lin-26 expression; lir-1 transcripts appear ubiquitous in early embryos, disappear, and then re-appear in later embryonic hypodermal and support cells; during larval development, a lir-1::lacZ fusion that should reflect expression of all transcripts is seen in nearly all cells with the exception of germ cells and post-L1 intestinal cells. | Paper_evidence | WBPaper00003532 | |||||
| WBPaper00003777 | |||||||||
| WBPaper00004780 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Dec 2006 00:00:00 | ||||||||
| Automated_description | Expressed in several structures, including head; intestinal cell; muscle cell; pharynx; and tail. Is predicted to encode a protein with the following domain: BED zinc finger. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS (14) | ||||||||
| Corresponding_transcript (15) | |||||||||
| Other_sequence (16) | |||||||||
| Associated_feature (50) | |||||||||
| Transcription_factor | WBTranscriptionFactor000432 | ||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern | Expr1324 | ||||||||
| Expr1327 | |||||||||
| Expr1020151 | |||||||||
| Expr1031428 | |||||||||
| Expr1148878 | |||||||||
| Expr2013224 | |||||||||
| Expr2031455 | |||||||||
| Drives_construct | WBCnstr00010220 | ||||||||
| WBCnstr00036265 | |||||||||
| Construct_product | WBCnstr00036265 | ||||||||
| Microarray_results (54) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction (51) | |||||||||
| Map_info | Map | II | Position | 0.5091 | |||||
| Positive | Positive_clone | F18A1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4479 | |||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | lir-1(mc33) is a 3 kb deletion within lir-1, which was isolated after TMP/UV mutagenesis by PCR-screening with primers in lir-1/lin-26. It is very tightly linked to a new deficiency named mcDf3. mcDf3 removes about 250-300 kb starting in the cosmid B0495, which is adjacent to F18A1 on it right. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
