WormBase Tree Display for Gene: WBGene00002207

WBGene00002207 SMap: S_parent: Sequence: B0302
  Identity: Version: 2
    Name: CGC_name: sid-3 Paper_evidence: WBPaper00041467
      Sequence_name: B0302.1
      Molecular_name: B0302.1a
        B0302.1a.1
        CE33506
        B0302.1b
        CE33548
        B0302.1b.1
        B0302.1c
      Other_name: kin-25
        CELE_B0302.1 Accession_evidence: NDB BX284606
      Public_name: sid-3
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 07 Nov 2012 16:57:03 WBPerson2970 Event: Acquires_merge: WBGene00004797
              Name_change: CGC_name: sid-3
                Other_name: kin-25
      Acquires_merge: WBGene00004797
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sid
    Allele (122)
    Strain: WBStrain00036067
      WBStrain00055665
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog (45)
    Paralog (44)
    Structured_description: Concise_description: sid-3 encodes a nonreceptor tyrosine kinase that is a member of the activated cdc-42-associated kinase (Ack) subfamily of cytoplasmic tyrosine kinases; in C. elegans sid-3 functions to regulate the import of dsRNA into cells, thus affecting the efficiency of RNA-mediated gene silencing (RNAi); SID-3 localizes to the cytoplasm. Paper_evidence: WBPaper00004273
            WBPaper00041467
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 02 Nov 2012 00:00:00
      Automated_description: Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytoplasm. Expressed in several structures, including excretory canal; intestine; phasmid neurons; rectal gland cell; and somatic cell. Is an ortholog of human TNK2 (tyrosine kinase non receptor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: B0302.1a
      B0302.1b
    Corresponding_CDS_history: B0302.1a:wp95
      B0302.1b:wp95
      B0302.1c:wp252
    Corresponding_transcript: B0302.1c
      B0302.1a.1
      B0302.1b.1
    Other_sequence: Dviv_isotig25152
      HBC15010_1
      Oden_isotig27081
      ES739658.1
      Oden_isotig22740
      JI164636.1
      FG619935.1
      CJC00290_1
    Associated_feature: WBsf648870
      WBsf1008825
      WBsf1008826
      WBsf1008827
      WBsf1024967
      WBsf1024968
  Experimental_info: RNAi_result: WBRNAi00038890 Inferred_automatically: RNAi_primary
      WBRNAi00112177 Inferred_automatically: RNAi_primary
      WBRNAi00038889 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr10570
      Expr11321
      Expr13515
      Expr15069
      Expr1017822
      Expr1031291
      Expr1143076
      Expr2015816
      Expr2034049
    Drives_construct: WBCnstr00015763
      WBCnstr00018771
      WBCnstr00018848
      WBCnstr00018849
      WBCnstr00037960
    Construct_product: WBCnstr00018848
      WBCnstr00018849
      WBCnstr00037960
      WBCnstr00039659
      WBCnstr00041965
    Regulate_expr_cluster: WBPaper00053020:sid-3(ok973)_downregulated
      WBPaper00053020:sid-3(ok973)_upregulated
    Microarray_results (32)
    Expression_cluster: WBPaper00032425:up_in_zfp-1
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033070:Elbe_downregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00040209:B.thuringiensis_upregulated_MY15
      WBPaper00040209:B.thuringiensis_upregulated_MY18
      WBPaper00040209:B.thuringiensis_upregulated_N2
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044736:flat_dev_expression
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050182:lmn-1(L535P)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050496:unc-39(hp701)_regulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051558:aging_regulated
      WBPaper00053020:sid-3(ok973)_downregulated
      WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058948:PA14_downregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061527:daf-1_17383-epc-1_15051
      WBPaper00062590:Aging_upregulated_coelomocyte
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      cgc4489_group_2
      WBPaper00025032:cluster_122
      WBPaper00030985:Erwinia_carotovora_upregulated
      WBPaper00037695:WC_5-day
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040821:Au-NP_regulated
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045960:L1-L4-lethargus_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
    Interaction (11)
  Map_info: Map: X Position: 24.0852 Error: 0.001211
    Positive: Positive_clone: B0302 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4685
        5259
    Pseudo_map_position
  Reference (29)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene