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WormBase Tree Display for Gene: WBGene00002203

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Name Class

WBGene00002203EvidencePaper_evidenceWBPaper00003768
SMapS_parentSequenceF46F2
IdentityVersion1
NameCGC_namekin-20
Sequence_nameF46F2.2
Molecular_name (22)
Other_nameCELE_F46F2.2Accession_evidenceNDBBX284606
Public_namekin-20
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkin
Allele (192)
StrainWBStrain00035739
RNASeq_FPKM (74)
GO_annotation (33)
Ortholog (40)
Paralog (93)
Structured_descriptionAutomated_descriptionEnables protein serine/threonine kinase activity. Involved in regulation of collateral sprouting and regulation of locomotion. Located in adherens junction and nucleus. Expressed in several structures, including hypodermal cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; advanced sleep phase syndrome 2; and invasive ductal carcinoma. Is an ortholog of human CSNK1E (casein kinase 1 epsilon) and TPTEP2-CSNK1E (TPTEP2-CSNK1E readthrough).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2452,HGNC:2453)
DOID:3008Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2453)
DOID:0110012Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2452)
Molecular_infoCorresponding_CDSF46F2.2a
F46F2.2b
F46F2.2c
F46F2.2d
F46F2.2e
F46F2.2f
F46F2.2g
Corresponding_CDS_historyF46F2.2:wp90
F46F2.2a:wp141
F46F2.2b:wp141
F46F2.2b:wp152
F46F2.2b:wp230
F46F2.2c:wp141
Corresponding_transcriptF46F2.2a.1
F46F2.2b.1
F46F2.2c.1
F46F2.2d.1
F46F2.2e.1
F46F2.2f.1
F46F2.2f.2
F46F2.2g.1
Other_sequence (56)
Associated_feature (27)
Experimental_infoRNAi_result (30)
Expr_pattern (13)
Drives_constructWBCnstr00011183
WBCnstr00041331
Construct_productWBCnstr00041331
Microarray_results (37)
Expression_clusterWBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037682:sma-2_upregulated
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:hypodermis_larva_enriched
WBPaper00037950:hypodermis_larva_SelectivelyEnriched
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(+)
WBPaper00050015:ifg-1(RNAi)_upregulated
WBPaper00050234:lin-28(RNAi)_upregulated
WBPaper00050344:ASER-neuron_enriched
WBPaper00050412:cco-1(RNAi)_upregulated_N2
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00051558:fog-2(q71)_regulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053599:female_vs_male_upregulated
WBPaper00053599:mitosis_vs_meiosis_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00054493:hpl-2(tm1489)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056218:daf-16(mu86)_upregulated_Day7
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
WBPaper00056284:ints-11(RNAi)_downregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056826:hmc_biased
WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
WBPaper00058691:set-2(bn129)_downregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00059471:EGL-43_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00060661:sensory-neuron_enriched
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00061466:nath-10(icb99)_upregulated
WBPaper00061466:nath-10(icb102)_upregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:tub-2_4713-daf-2_5288
WBPaper00061527:uggt-1_21889-tag-320_20312
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062520:qui-1(db104)_upregulated
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064315:met-1(bn200)_downregulated_PGCs
WBPaper00064532:pals-25(icb98)_downregulated
WBPaper00064716:paraquat_downregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
cgc4386_cluster_6_6
cgc4489_group_8
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00027111:rrf-2(ok210)_upregulated
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00031832:slr-2_regulated
WBPaper00032948:FedUp
WBPaper00034661:AgNPs_downregulated
WBPaper00035588:alg-1(-)_upregulated
WBPaper00040210:Chlorpyrifos_16C_regulated
WBPaper00040876:mir-35_downregulated
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045960:L1-L4-lethargus_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:Cluster_B
Interaction (171)
Map_infoMapXPosition22.3134Error0.007661
PositivePositive_cloneF46F2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4459
Pseudo_map_position
Reference (26)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene