WormBase Tree Display for Gene: WBGene00002200
expand all nodes | collapse all nodes | view schema
| WBGene00002200 | SMap | S_parent | Sequence | M176 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | kin-16 | |||||||
| Sequence_name | M176.7 | ||||||||
| Molecular_name | M176.7 | ||||||||
| M176.7.1 | |||||||||
| CE12472 | |||||||||
| Other_name | CELE_M176.7 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | kin-16 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kin | ||||||||
| Allele (36) | |||||||||
| Legacy_information | [C.elegansII] Tc1 insertion : retarded development? Encodes predicted tyrosine kinase with transmembrane domain, no large extracellular domain. Related to kin-15. [Morgan and Greenwald 1993; WR] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP2428 | ||||||||
| Ortholog (35) | |||||||||
| Paralog (33) | |||||||||
| Structured_description | Concise_description | kin-16 encodes a novel receptor protein tyrosine kinase; like kin-15, with which it is cotranscribed, kin-16 encodes a protein that displays some unusual features, including a very small extracellular domain (50 amino acids) that lacks a cysteine-rich region typical of ligand-binding domains of known receptor tyrosine kinases, an unusual amino acid substitution in the subdomain VI motif, and a lack of typical autophosphorylation sites in the kinase insert and C-terminal domains; a kin-16 reporter is first detected in young L1 larvae in the hyp7 syncytium; later expression is detected in ventral and lateral cells that fuse with hyp7 as well as in the more anterior hyp6 syncytium late in development; this distinct expression pattern suggests that kin-16 may also play a role in development of the hypodermal syncytium and perhaps be involved in cell-cell interactions regulating postembryonic cell fusions. | Paper_evidence | WBPaper00001825 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 09 Nov 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hyp6 and hyp7 syncytium. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | M176.7 | |||||||
| Corresponding_transcript | M176.7.1 | ||||||||
| Other_sequence | CBC10712_1 | ||||||||
| BMC01784_1 | |||||||||
| Oden_isotig14194 | |||||||||
| Associated_feature | WBsf223652 | ||||||||
| WBsf223653 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00027615 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00051001 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1521 | ||||||||
| Expr1026301 | |||||||||
| Expr1154710 | |||||||||
| Expr2012929 | |||||||||
| Drives_construct | WBCnstr00010320 | ||||||||
| WBCnstr00036391 | |||||||||
| Construct_product | WBCnstr00010320 | ||||||||
| WBCnstr00036391 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (151) | |||||||||
| Interaction (40) | |||||||||
| Map_info | Map | II | Position | 1.43234 | Error | 0.005023 | |||
| Positive | Positive_clone | C07A2 | |||||||
| M176 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
