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WormBase Tree Display for Gene: WBGene00002200

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Name Class

WBGene00002200SMapS_parentSequenceM176
IdentityVersion1
NameCGC_namekin-16
Sequence_nameM176.7
Molecular_nameM176.7
M176.7.1
CE12472
Other_nameCELE_M176.7Accession_evidenceNDBBX284602
Public_namekin-16
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkin
Allele (36)
Legacy_information[C.elegansII] Tc1 insertion : retarded development? Encodes predicted tyrosine kinase with transmembrane domain, no large extracellular domain. Related to kin-15. [Morgan and Greenwald 1993; WR]
RNASeq_FPKM (74)
GO_annotation (17)
Contained_in_operonCEOP2428
Ortholog (35)
ParalogWBGene00000289Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000898Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001184Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002195Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002199Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006868Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002299Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004740Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015087Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010342Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00008599Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020678Caenorhabditis elegansFrom_analysisPanther
WBGene00003007Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00017381Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011339Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00017310Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016059Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00008711Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006896Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006897Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021745Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003862Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011169Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002205Caenorhabditis elegansFrom_analysisPanther
WBGene00002211Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00012270Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003863Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011168Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006894Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006895Caenorhabditis elegansFrom_analysisPanther
WBGene00020966Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020504Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020106Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionkin-16 encodes a novel receptor protein tyrosine kinase; like kin-15, with which it is cotranscribed, kin-16 encodes a protein that displays some unusual features, including a very small extracellular domain (50 amino acids) that lacks a cysteine-rich region typical of ligand-binding domains of known receptor tyrosine kinases, an unusual amino acid substitution in the subdomain VI motif, and a lack of typical autophosphorylation sites in the kinase insert and C-terminal domains; a kin-16 reporter is first detected in young L1 larvae in the hyp7 syncytium; later expression is detected in ventral and lateral cells that fuse with hyp7 as well as in the more anterior hyp6 syncytium late in development; this distinct expression pattern suggests that kin-16 may also play a role in development of the hypodermal syncytium and perhaps be involved in cell-cell interactions regulating postembryonic cell fusions.Paper_evidenceWBPaper00001825
Curator_confirmedWBPerson1843
Date_last_updated09 Nov 2007 00:00:00
Automated_descriptionPredicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hyp6 and hyp7 syncytium.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSM176.7
Corresponding_transcriptM176.7.1
Other_sequenceCBC10712_1
BMC01784_1
Oden_isotig14194
Associated_featureWBsf223652
WBsf223653
Experimental_infoRNAi_resultWBRNAi00027615Inferred_automaticallyRNAi_primary
WBRNAi00051001Inferred_automaticallyRNAi_primary
Expr_patternExpr1521
Expr1026301
Expr1154710
Expr2012929
Drives_constructWBCnstr00010320
WBCnstr00036391
Construct_productWBCnstr00010320
WBCnstr00036391
Microarray_results (17)
Expression_cluster (151)
Interaction (40)
Map_infoMapIIPosition1.43234Error0.005023
PositivePositive_cloneC07A2
M176Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (21)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene