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WormBase Tree Display for Gene: WBGene00002200

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Name Class

WBGene00002200SMapS_parentSequenceM176
IdentityVersion1
NameCGC_namekin-16
Sequence_nameM176.7
Molecular_nameM176.7
M176.7.1
CE12472
Other_nameCELE_M176.7Accession_evidenceNDBBX284602
Public_namekin-16
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkin
Allele (36)
Legacy_information[C.elegansII] Tc1 insertion : retarded development? Encodes predicted tyrosine kinase with transmembrane domain, no large extracellular domain. Related to kin-15. [Morgan and Greenwald 1993; WR]
RNASeq_FPKM (74)
GO_annotation (17)
Contained_in_operonCEOP2428
Ortholog (35)
Paralog (33)
Structured_descriptionConcise_descriptionkin-16 encodes a novel receptor protein tyrosine kinase; like kin-15, with which it is cotranscribed, kin-16 encodes a protein that displays some unusual features, including a very small extracellular domain (50 amino acids) that lacks a cysteine-rich region typical of ligand-binding domains of known receptor tyrosine kinases, an unusual amino acid substitution in the subdomain VI motif, and a lack of typical autophosphorylation sites in the kinase insert and C-terminal domains; a kin-16 reporter is first detected in young L1 larvae in the hyp7 syncytium; later expression is detected in ventral and lateral cells that fuse with hyp7 as well as in the more anterior hyp6 syncytium late in development; this distinct expression pattern suggests that kin-16 may also play a role in development of the hypodermal syncytium and perhaps be involved in cell-cell interactions regulating postembryonic cell fusions.Paper_evidenceWBPaper00001825
Curator_confirmedWBPerson1843
Date_last_updated09 Nov 2007 00:00:00
Automated_descriptionPredicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hyp6 and hyp7 syncytium.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSM176.7
Corresponding_transcriptM176.7.1
Other_sequenceCBC10712_1
BMC01784_1
Oden_isotig14194
Associated_featureWBsf223652
WBsf223653
Experimental_infoRNAi_resultWBRNAi00027615Inferred_automaticallyRNAi_primary
WBRNAi00051001Inferred_automaticallyRNAi_primary
Expr_patternExpr1521
Expr1026301
Expr1154710
Expr2012929
Drives_constructWBCnstr00010320
WBCnstr00036391
Construct_productWBCnstr00010320
WBCnstr00036391
Microarray_results (17)
Expression_cluster (151)
InteractionWBInteraction000134056
WBInteraction000209426
WBInteraction000227888
WBInteraction000262532
WBInteraction000285831
WBInteraction000295484
WBInteraction000322457
WBInteraction000324795
WBInteraction000328061
WBInteraction000329472
WBInteraction000340005
WBInteraction000352700
WBInteraction000360113
WBInteraction000369527
WBInteraction000375635
WBInteraction000380366
WBInteraction000382217
WBInteraction000382318
WBInteraction000391928
WBInteraction000395616
WBInteraction000400489
WBInteraction000405717
WBInteraction000413168
WBInteraction000422762
WBInteraction000424017
WBInteraction000426978
WBInteraction000431159
WBInteraction000434036
WBInteraction000435745
WBInteraction000436931
WBInteraction000440182
WBInteraction000443011
WBInteraction000445159
WBInteraction000446285
WBInteraction000447918
WBInteraction000450188
WBInteraction000452069
WBInteraction000452835
WBInteraction000454453
WBInteraction000456232
Map_infoMapIIPosition1.43234Error0.005023
PositivePositive_cloneC07A2
M176Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (21)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene