WormBase Tree Display for Gene: WBGene00002177
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| WBGene00002177 | SMap | S_parent | Sequence | F35C8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | jkk-1 | |||||||
| Sequence_name | F35C8.3 | ||||||||
| Molecular_name | F35C8.3 | ||||||||
| F35C8.3.1 | |||||||||
| CE24941 | |||||||||
| F35C8.3.2 | |||||||||
| Other_name | sek-2 | ||||||||
| CELE_F35C8.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | jkk-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | jkk | ||||||||
| Allele (123) | |||||||||
| Possibly_affected_by | WBVar02158462 | ||||||||
| Strain | WBStrain00024034 | ||||||||
| WBStrain00052747 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Ortholog (32) | |||||||||
| Paralog (25) | |||||||||
| Structured_description | Concise_description | jkk-1 encodes a member of the MAP kinase kinase superfamily that affects synaptic vesicle localization and is required in type-D motor neurons for normal locomotion; can function in the Hog1 MAP kinase pathway I in yeast as an activator of JNK and is expressed in most neurons | Paper_evidence | WBPaper00003607 | |||||
| WBPaper00004889 | |||||||||
| WBPaper00005014 | |||||||||
| WBPaper00018908 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 09 Aug 2004 00:00:00 | ||||||||
| Automated_description | Enables JUN kinase kinase activity. Involved in hyperosmotic response and locomotion. Located in axon; cytoplasm; and neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K7 (mitogen-activated protein kinase kinase 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3905 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6847) | ||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6847) | ||||||
| DOID:8634 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6847) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6847) | ||||||
| DOID:234 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6847) | ||||||
| Molecular_info | Corresponding_CDS | F35C8.3 | |||||||
| Corresponding_transcript | F35C8.3.1 | ||||||||
| F35C8.3.2 | |||||||||
| Associated_feature | WBsf648105 | ||||||||
| WBsf662781 | |||||||||
| WBsf662782 | |||||||||
| WBsf1005250 | |||||||||
| WBsf1005251 | |||||||||
| WBsf1022942 | |||||||||
| WBsf1022943 | |||||||||
| WBsf235713 | |||||||||
| WBsf235714 | |||||||||
| WBsf235715 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00113189 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00046310 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014313 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00069430 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112959 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028244 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046315 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00094592 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002050 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1228 | ||||||||
| Expr11255 | |||||||||
| Expr1014081 | |||||||||
| Expr1031272 | |||||||||
| Expr1150198 | |||||||||
| Expr2012884 | |||||||||
| Expr2031118 | |||||||||
| Drives_construct | WBCnstr00010164 | ||||||||
| WBCnstr00015940 | |||||||||
| WBCnstr00036408 | |||||||||
| Construct_product | WBCnstr00000778 | ||||||||
| WBCnstr00010164 | |||||||||
| WBCnstr00018063 | |||||||||
| WBCnstr00018392 | |||||||||
| WBCnstr00036408 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (162) | |||||||||
| Interaction (199) | |||||||||
| WBProcess | WBbiopr:00000052 | ||||||||
| Map_info | Map | X | Position | -5.40375 | Error | 0.023352 | |||
| Positive | Positive_clone | F35C8 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4449 | |||||||
| 4261 | |||||||||
| 4780 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (54) | |||||||||
| Picture | WBPicture0000013081 | ||||||||
| Remark | sequence and product from N Hisamoto | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
