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WormBase Tree Display for Gene: WBGene00002177

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Name Class

WBGene00002177SMapS_parentSequenceF35C8
IdentityVersion1
NameCGC_namejkk-1
Sequence_nameF35C8.3
Molecular_nameF35C8.3
F35C8.3.1
CE24941
F35C8.3.2
Other_namesek-2
CELE_F35C8.3Accession_evidenceNDBBX284606
Public_namejkk-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classjkk
AlleleWBVar00078973
WBVar00078974
WBVar00078975
WBVar00078976
WBVar00078977
WBVar01980647
WBVar00078978
WBVar01549831
WBVar01549832
WBVar00078979
WBVar00078980
WBVar01549833
WBVar00078981
WBVar01549834
WBVar01549835
WBVar00078982
WBVar00078983
WBVar00078984
WBVar01879254
WBVar01879255
WBVar01879256
WBVar01879257
WBVar01879258
WBVar01879259
WBVar01495492
WBVar00503585
WBVar00503586
WBVar00503587
WBVar00503588
WBVar00503589
WBVar00503590
WBVar00503591
WBVar00274254
WBVar00503592
WBVar00274255
WBVar00503593
WBVar00503594
WBVar00503595
WBVar00503596
WBVar00503597
WBVar02139289
WBVar02063801
WBVar02063802
WBVar01830529
WBVar01830530
WBVar00088240
WBVar01146888
WBVar01146889
WBVar01146890
WBVar01146891
WBVar01146892
WBVar01146893
WBVar01601744
WBVar01146894
WBVar02046409
WBVar01601745
WBVar02046410
WBVar01146895
WBVar01601746
WBVar01146896
WBVar01146897
WBVar01146898
WBVar00026701
WBVar01468895
WBVar01146899
WBVar01468896
WBVar01146900
WBVar01468898
WBVar01146901
WBVar01146902
WBVar01146903
WBVar01146904
WBVar01146905
WBVar01945395
WBVar01146906
WBVar01945396
WBVar01146907
WBVar00264368
WBVar01146908
WBVar01758362
WBVar01146909
WBVar01146910
WBVar01146911
WBVar01146912
WBVar01146913
WBVar01146914
WBVar01146915
WBVar01486946
WBVar01146916
WBVar01146917
WBVar01486947
WBVar01486948
WBVar01146918
WBVar01146919
WBVar01146920
WBVar01146921
WBVar01146922
WBVar01146923
WBVar01146924
WBVar01146925
WBVar01146926
WBVar01146927
WBVar01146928
WBVar01146929
WBVar01146930
WBVar01146931
WBVar01146932
WBVar00255373
WBVar01146933
WBVar01815598
WBVar01146934
WBVar01815599
WBVar01146935
WBVar01146936
WBVar01146937
WBVar01146938
WBVar01146939
WBVar01499683
WBVar01499684
WBVar01819870
WBVar01819871
WBVar01819872
WBVar01500067
Possibly_affected_byWBVar02158462
StrainWBStrain00024034
WBStrain00052747
RNASeq_FPKM (74)
GO_annotation (29)
Ortholog (32)
Paralog (25)
Structured_descriptionConcise_descriptionjkk-1 encodes a member of the MAP kinase kinase superfamily that affects synaptic vesicle localization and is required in type-D motor neurons for normal locomotion; can function in the Hog1 MAP kinase pathway I in yeast as an activator of JNK and is expressed in most neuronsPaper_evidenceWBPaper00003607
WBPaper00004889
WBPaper00005014
WBPaper00018908
Curator_confirmedWBPerson48
Date_last_updated09 Aug 2004 00:00:00
Automated_descriptionEnables JUN kinase kinase activity. Involved in hyperosmotic response and locomotion. Located in axon; cytoplasm; and neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K7 (mitogen-activated protein kinase kinase 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3905Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6847)
DOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6847)
DOID:8634Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6847)
DOID:3910Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6847)
DOID:234Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6847)
Molecular_infoCorresponding_CDSF35C8.3
Corresponding_transcriptF35C8.3.1
F35C8.3.2
Associated_featureWBsf648105
WBsf662781
WBsf662782
WBsf1005250
WBsf1005251
WBsf1022942
WBsf1022943
WBsf235713
WBsf235714
WBsf235715
Experimental_infoRNAi_resultWBRNAi00113189Inferred_automaticallyRNAi_primary
WBRNAi00046310Inferred_automaticallyRNAi_primary
WBRNAi00014313Inferred_automaticallyRNAi_primary
WBRNAi00069430Inferred_automaticallyRNAi_primary
WBRNAi00112959Inferred_automaticallyRNAi_primary
WBRNAi00028244Inferred_automaticallyRNAi_primary
WBRNAi00046315Inferred_automaticallyRNAi_primary
WBRNAi00094592Inferred_automaticallyRNAi_primary
WBRNAi00002050Inferred_automaticallyRNAi_primary
Expr_patternExpr1228
Expr11255
Expr1014081
Expr1031272
Expr1150198
Expr2012884
Expr2031118
Drives_constructWBCnstr00010164
WBCnstr00015940
WBCnstr00036408
Construct_productWBCnstr00000778
WBCnstr00010164
WBCnstr00018063
WBCnstr00018392
WBCnstr00036408
Microarray_results (26)
Expression_cluster (162)
Interaction (199)
WBProcessWBbiopr:00000052
Map_infoMapXPosition-5.40375Error0.023352
PositivePositive_cloneF35C8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4449
4261
4780
Pseudo_map_position
Reference (54)
PictureWBPicture0000013081
Remarksequence and product from N Hisamoto
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene