WormBase Tree Display for Gene: WBGene00002090
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WBGene00002090 | Evidence | Paper_evidence (2) | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | ZK1251 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | ins-7 | Person_evidence | WBPerson339 | |||||
Sequence_name | ZK1251.2 | ||||||||
Molecular_name | ZK1251.2a | ||||||||
ZK1251.2a.1 | |||||||||
CE03849 | |||||||||
ZK1251.2b | |||||||||
CE47202 | |||||||||
ZK1251.2b.1 | |||||||||
Other_name | CELE_ZK1251.2 | Accession_evidence | NDB | BX284604 | |||||
Public_name | ins-7 | ||||||||
DB_info | Database | AceView | gene | 4K446 | |||||
WormQTL | gene | WBGene00002090 | |||||||
WormFlux | gene | WBGene00002090 | |||||||
NDB | locus_tag | CELE_ZK1251.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00002090|UniProtKB=Q23430 | |||||||
family | PTHR33893 | ||||||||
NCBI | gene | 191688 | |||||||
RefSeq | protein | NM_001268489.3 | |||||||
NM_001268488.3 | |||||||||
SwissProt | UniProtAcc | Q23430 | |||||||
TrEMBL | UniProtAcc | H9G2S9 | |||||||
UniProt_GCRP | UniProtAcc | Q23430 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ins | ||||||||
Allele (14) | |||||||||
Legacy_information | [Ferguson K] ins for INSulin related. No mutants known. | ||||||||
Strain | WBStrain00032086 | ||||||||
WBStrain00048368 | |||||||||
WBStrain00048365 | |||||||||
WBStrain00048374 | |||||||||
WBStrain00048360 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00023681 | ||||||||
00023682 | |||||||||
00023683 | |||||||||
00023684 | |||||||||
00078437 | |||||||||
00110010 | |||||||||
00110011 | |||||||||
Ortholog | WBGene00053993 | Caenorhabditis remanei | From_analysis | OMA | |||||
WBGene00083908 | Caenorhabditis remanei | From_analysis | OMA | ||||||
WBGene00140898 | Caenorhabditis brenneri | From_analysis | WormBase-Compara | ||||||
WBGene00158728 | Caenorhabditis brenneri | From_analysis | WormBase-Compara | ||||||
CSP40.g8612 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
Csp11.Scaffold629.g16423 | Caenorhabditis tropicalis | From_analysis | WormBase-Compara | ||||||
Csp5_scaffold_00132.g5201 | Caenorhabditis sinica | From_analysis | WormBase-Compara | ||||||
chrIV_pilon.g11377 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Paralog | WBGene00000920 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WBGene00002085 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002086 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002087 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002088 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002089 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002091 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00002102 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002115 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002098 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00002092 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00002121 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002107 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002113 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002114 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002110 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002116 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002112 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00002108 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity. | Paper_evidence (3) | ||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 13 Dec 2010 00:00:00 | ||||||||
Automated_description | Predicted to enable hormone activity. Involved in olfactory learning. Predicted to be located in extracellular region and membrane. Expressed in several structures, including distal tip cell; egg-laying apparatus; head muscle; neurons; and somatic nervous system. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | ZK1251.2a | |||||||
ZK1251.2b | |||||||||
Corresponding_transcript | ZK1251.2a.1 | ||||||||
ZK1251.2b.1 | |||||||||
Associated_feature | WBsf230601 | ||||||||
Experimental_info | RNAi_result (23) | ||||||||
Expr_pattern | Expr869 | ||||||||
Expr7824 | |||||||||
Expr10634 | |||||||||
Expr10845 | |||||||||
Expr11930 | |||||||||
Expr1014616 | |||||||||
Expr1162617 | |||||||||
Expr2012778 | |||||||||
Expr2031017 | |||||||||
Drives_construct | WBCnstr00012946 | ||||||||
WBCnstr00013458 | |||||||||
WBCnstr00017002 | |||||||||
WBCnstr00017780 | |||||||||
WBCnstr00019811 | |||||||||
WBCnstr00020764 | |||||||||
WBCnstr00036462 | |||||||||
Construct_product | WBCnstr00016055 | ||||||||
WBCnstr00020764 | |||||||||
WBCnstr00036462 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (234) | |||||||||
Interaction (153) | |||||||||
WBProcess | WBbiopr:00000001 | ||||||||
WBbiopr:00000008 | |||||||||
WBbiopr:00000039 | |||||||||
Map_info | Map | IV | Position | 4.35256 | Error | 0.001133 | |||
Positive | Positive_clone | ZK1251 | Author_evidence | Ferguson KC | |||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | Multi_point | 5260 | |||||||
5454 | |||||||||
Pseudo_map_position | |||||||||
Reference (61) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |