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WormBase Tree Display for Gene: WBGene00002090

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Name Class

WBGene00002090EvidencePaper_evidenceWBPaper00003057
WBPaper00004623
SMapS_parentSequenceZK1251
IdentityVersion1
NameCGC_nameins-7Person_evidenceWBPerson339
Sequence_nameZK1251.2
Molecular_nameZK1251.2a
ZK1251.2a.1
CE03849
ZK1251.2b
CE47202
ZK1251.2b.1
Other_nameCELE_ZK1251.2Accession_evidenceNDBBX284604
Public_nameins-7
DB_infoDatabaseAceViewgene4K446
WormQTLgeneWBGene00002090
WormFluxgeneWBGene00002090
NDBlocus_tagCELE_ZK1251.2
PanthergeneCAEEL|WormBase=WBGene00002090|UniProtKB=Q23430
familyPTHR33893
NCBIgene191688
RefSeqproteinNM_001268489.3
NM_001268488.3
SwissProtUniProtAccQ23430
TrEMBLUniProtAccH9G2S9
UniProt_GCRPUniProtAccQ23430
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classins
Allele (14)
Legacy_information[Ferguson K] ins for INSulin related. No mutants known.
StrainWBStrain00032086
WBStrain00048368
WBStrain00048365
WBStrain00048374
WBStrain00048360
RNASeq_FPKM (74)
GO_annotation00023681
00023682
00023683
00023684
00078437
00110010
00110011
OrthologWBGene00053993Caenorhabditis remaneiFrom_analysisOMA
WBGene00083908Caenorhabditis remaneiFrom_analysisOMA
WBGene00140898Caenorhabditis brenneriFrom_analysisWormBase-Compara
WBGene00158728Caenorhabditis brenneriFrom_analysisWormBase-Compara
CSP40.g8612Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Csp11.Scaffold629.g16423Caenorhabditis tropicalisFrom_analysisWormBase-Compara
Csp5_scaffold_00132.g5201Caenorhabditis sinicaFrom_analysisWormBase-Compara
chrIV_pilon.g11377Caenorhabditis elegansFrom_analysisWormBase-Compara
Paralog (19)
Structured_descriptionConcise_descriptionins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.Paper_evidenceWBPaper00004623
WBPaper00005976
WBPaper00029214
Curator_confirmedWBPerson1843
Date_last_updated13 Dec 2010 00:00:00
Automated_descriptionPredicted to enable hormone activity. Involved in olfactory learning. Predicted to be located in extracellular region and membrane. Expressed in several structures, including distal tip cell; egg-laying apparatus; head muscle; neurons; and somatic nervous system.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK1251.2a
ZK1251.2b
Corresponding_transcriptZK1251.2a.1
ZK1251.2b.1
Associated_featureWBsf230601
Experimental_infoRNAi_resultWBRNAi00107985Inferred_automaticallyRNAi_primary
WBRNAi00063222Inferred_automaticallyRNAi_primary
WBRNAi00082886Inferred_automaticallyRNAi_primary
WBRNAi00063221Inferred_automaticallyRNAi_primary
WBRNAi00107989Inferred_automaticallyRNAi_primary
WBRNAi00095390Inferred_automaticallyRNAi_primary
WBRNAi00021852Inferred_automaticallyRNAi_primary
WBRNAi00107990Inferred_automaticallyRNAi_primary
WBRNAi00069846Inferred_automaticallyRNAi_primary
WBRNAi00059199Inferred_automaticallyRNAi_primary
WBRNAi00107986Inferred_automaticallyRNAi_primary
WBRNAi00095389Inferred_automaticallyRNAi_primary
WBRNAi00095391Inferred_automaticallyRNAi_primary
WBRNAi00038188Inferred_automaticallyRNAi_primary
WBRNAi00082887Inferred_automaticallyRNAi_primary
WBRNAi00059200Inferred_automaticallyRNAi_primary
WBRNAi00094545Inferred_automaticallyRNAi_primary
WBRNAi00069853Inferred_automaticallyRNAi_primary
WBRNAi00021853Inferred_automaticallyRNAi_primary
WBRNAi00070106Inferred_automaticallyRNAi_primary
WBRNAi00107952Inferred_automaticallyRNAi_primary
WBRNAi00069852Inferred_automaticallyRNAi_primary
WBRNAi00095388Inferred_automaticallyRNAi_primary
Expr_patternExpr869
Expr7824
Expr10634
Expr10845
Expr11930
Expr1014616
Expr1162617
Expr2012778
Expr2031017
Drives_constructWBCnstr00012946
WBCnstr00013458
WBCnstr00017002
WBCnstr00017780
WBCnstr00019811
WBCnstr00020764
WBCnstr00036462
Construct_productWBCnstr00016055
WBCnstr00020764
WBCnstr00036462
Microarray_results (18)
Expression_cluster (234)
InteractionWBInteraction000004955
WBInteraction000005561
WBInteraction000005611
WBInteraction000259776
WBInteraction000285310
WBInteraction000317595
WBInteraction000336565
WBInteraction000341580
WBInteraction000344276
WBInteraction000345721
WBInteraction000346778
WBInteraction000350353
WBInteraction000363213
WBInteraction000368626
WBInteraction000369328
WBInteraction000370613
WBInteraction000376641
WBInteraction000392272
WBInteraction000398952
WBInteraction000399044
WBInteraction000401383
WBInteraction000401964
WBInteraction000402205
WBInteraction000404740
WBInteraction000407171
WBInteraction000410285
WBInteraction000421687
WBInteraction000433479
WBInteraction000439102
WBInteraction000448985
WBInteraction000455367
WBInteraction000456171
WBInteraction000458228
WBInteraction000503343
WBInteraction000503405
WBInteraction000503406
WBInteraction000504110
WBInteraction000504685
WBInteraction000504687
WBInteraction000519452
WBInteraction000519498
WBInteraction000519499
WBInteraction000519500
WBInteraction000519970
WBInteraction000520965
WBInteraction000521998
WBInteraction000523975
WBInteraction000524332
WBInteraction000525198
WBInteraction000534755
WBInteraction000535581
WBInteraction000535620
WBInteraction000535659
WBInteraction000535692
WBInteraction000535693
WBInteraction000535694
WBInteraction000535695
WBInteraction000535696
WBInteraction000535697
WBInteraction000535698
WBInteraction000535699
WBInteraction000535700
WBInteraction000535701
WBInteraction000535702
WBInteraction000535703
WBInteraction000535704
WBInteraction000535705
WBInteraction000535706
WBInteraction000535707
WBInteraction000535708
WBInteraction000535709
WBInteraction000535710
WBInteraction000535711
WBInteraction000535712
WBInteraction000535713
WBInteraction000535714
WBInteraction000535715
WBInteraction000535716
WBInteraction000535717
WBInteraction000535718
WBInteraction000535719
WBInteraction000535720
WBInteraction000535721
WBInteraction000535722
WBInteraction000535723
WBInteraction000535724
WBInteraction000535725
WBInteraction000535726
WBInteraction000535727
WBInteraction000535728
WBInteraction000535729
WBInteraction000535730
WBInteraction000535738
WBInteraction000535777
WBInteraction000535816
WBInteraction000535855
WBInteraction000535894
WBInteraction000535933
WBInteraction000536079
WBInteraction000536082
WBInteraction000541640
WBInteraction000541802
WBInteraction000541866
WBInteraction000541867
WBInteraction000541868
WBInteraction000541869
WBInteraction000541870
WBInteraction000541871
WBInteraction000542521
WBInteraction000542888
WBInteraction000543170
WBInteraction000543172
WBInteraction000543173
WBInteraction000543177
WBInteraction000543182
WBInteraction000543184
WBInteraction000543186
WBInteraction000543189
WBInteraction000543190
WBInteraction000543191
WBInteraction000543194
WBInteraction000543195
WBInteraction000543212
WBInteraction000543214
WBInteraction000543215
WBInteraction000543216
WBInteraction000543217
WBInteraction000543218
WBInteraction000543219
WBInteraction000543221
WBInteraction000543222
WBInteraction000543223
WBInteraction000543224
WBInteraction000543225
WBInteraction000543226
WBInteraction000543227
WBInteraction000543229
WBInteraction000543230
WBInteraction000543231
WBInteraction000543232
WBInteraction000543233
WBInteraction000543235
WBInteraction000543237
WBInteraction000543238
WBInteraction000543240
WBInteraction000543241
WBInteraction000543242
WBInteraction000543244
WBInteraction000543246
WBInteraction000543247
WBInteraction000543249
WBInteraction000543259
WBInteraction000543260
WBProcessWBbiopr:00000001
WBbiopr:00000008
WBbiopr:00000039
Map_infoMapIVPosition4.35256Error0.001133
PositivePositive_cloneZK1251Author_evidenceFerguson KC
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5260
5454
Pseudo_map_position
Reference (61)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene