WormBase Tree Display for Gene: WBGene00002066
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| WBGene00002066 | Evidence | Person_evidence | WBPerson1666 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | M110 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ifg-1 | Person_evidence | WBPerson1666 | |||||
| Sequence_name | M110.4 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | CELE_M110.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | ifg-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifg | ||||||||
| Allele (76) | |||||||||
| Strain | WBStrain00001270 | ||||||||
| WBStrain00024079 | |||||||||
| WBStrain00036060 | |||||||||
| WBStrain00024080 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00003642 | ||||||||
| 00003643 | |||||||||
| 00003644 | |||||||||
| 00003645 | |||||||||
| 00003646 | |||||||||
| 00006169 | |||||||||
| 00006170 | |||||||||
| 00109964 | |||||||||
| 00109965 | |||||||||
| Ortholog (59) | |||||||||
| Structured_description | Concise_description | ifg-1 encodes, by alternative splicing, two orthologs of the translation initiation factor 4F, ribosome/mRNA-bridging subunit (eIF-4G); by homology, IFG-1 is predicted to function in poly(A) tail-dependent translation initiation; loss of ifg-1 activity in adult animals extends lifespan. | Paper_evidence | WBPaper00005068 | |||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| WBPaper00029008 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 25 Jul 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable mRNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Located in cytosol. Part of eukaryotic translation initiation factor 4F complex. Expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in late onset Parkinson's disease. Is an ortholog of human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060892 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3296) | ||||
| Molecular_info | Corresponding_CDS | M110.4a | |||||||
| M110.4b | |||||||||
| M110.4c | |||||||||
| M110.4d | |||||||||
| M110.4e | |||||||||
| Corresponding_CDS_history | M110.4d:wp270 | ||||||||
| M110.4e:wp261 | |||||||||
| Corresponding_transcript | M110.4a.1 | ||||||||
| M110.4b.1 | |||||||||
| M110.4c.1 | |||||||||
| M110.4d.1 | |||||||||
| M110.4e.1 | |||||||||
| Other_sequence | CGC01168_1 | ||||||||
| CBC07565_1 | |||||||||
| Associated_feature (24) | |||||||||
| Experimental_info | RNAi_result (88) | ||||||||
| Expr_pattern | Chronogram1630 | ||||||||
| Expr2003 | |||||||||
| Expr4023 | |||||||||
| Expr1021338 | |||||||||
| Expr1031219 | |||||||||
| Expr1154648 | |||||||||
| Expr2012694 | |||||||||
| Expr2030930 | |||||||||
| Drives_construct | WBCnstr00002165 | ||||||||
| WBCnstr00036481 | |||||||||
| Construct_product | WBCnstr00036481 | ||||||||
| Regulate_expr_cluster | WBPaper00039835:ifg-1_downregulated | ||||||||
| WBPaper00039835:ifg-1_upregulated | |||||||||
| WBPaper00050015:ifg-1(RNAi)_downregulated | |||||||||
| WBPaper00050015:ifg-1(RNAi)_upregulated | |||||||||
| Antibody | WBAntibody00001408 | ||||||||
| WBAntibody00001409 | |||||||||
| WBAntibody00001410 | |||||||||
| WBAntibody00001654 | |||||||||
| Microarray_results (36) | |||||||||
| Expression_cluster (170) | |||||||||
| Interaction (263) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | II | Position | 0.750204 | Error | 0.00036 | |||
| Positive | Positive_clone | M110 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5120 | |||||||
| 4617 | |||||||||
| 5014 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (33) | |||||||||
| Remark | ifg-1 related ESTs: Longest EST's: yk450c12, yk1009e02. Many other partial EST's. | Person_evidence | WBPerson1666 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
