WormBase Tree Display for Gene: WBGene00002050
expand all nodes | collapse all nodes | view schema
| WBGene00002050 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ifa-1 | Person_evidence | WBPerson105 | |||||
| WBPerson293 | |||||||||
| Sequence_name | F38B2.1 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | Cel IF A1 | Accession_evidence | EMBL | X70834 | |||||
| CelIF a1 | |||||||||
| A1 | Paper_evidence | WBPaper00006137 | |||||||
| CELE_F38B2.1 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ifa-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifa | ||||||||
| Allele (77) | |||||||||
| Strain | WBStrain00036052 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (65) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum. | Paper_evidence | WBPaper00001981 | |||||
| WBPaper00004761 | |||||||||
| WBPaper00006137 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in intermediate filament. Expressed in several structures, including egg-laying apparatus; excretory cell; neurons; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | F38B2.1a | |||||||
| F38B2.1b | |||||||||
| F38B2.1c | |||||||||
| F38B2.1d | |||||||||
| F38B2.1e | |||||||||
| Corresponding_CDS_history | F38B2.1:wp83 | ||||||||
| Corresponding_transcript | F38B2.1a.1 | ||||||||
| F38B2.1b.1 | |||||||||
| F38B2.1c.1 | |||||||||
| F38B2.1d.1 | |||||||||
| F38B2.1e.1 | |||||||||
| Other_sequence (241) | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result (48) | ||||||||
| Expr_pattern | Expr1495 | ||||||||
| Expr2762 | |||||||||
| Expr1013956 | |||||||||
| Expr1031203 | |||||||||
| Expr1150559 | |||||||||
| Expr2012676 | |||||||||
| Expr2030912 | |||||||||
| Drives_construct | WBCnstr00010937 | ||||||||
| WBCnstr00036494 | |||||||||
| Construct_product | WBCnstr00010937 | ||||||||
| WBCnstr00036494 | |||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (212) | |||||||||
| Interaction (72) | |||||||||
| Map_info | Map | X | Position | 2.86537 | Error | 0.001386 | |||
| Positive | Positive_clone | F38B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4945 | |||||||
| 4421 | |||||||||
| 4442 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
