WormBase Tree Display for Gene: WBGene00002050
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| WBGene00002050 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ifa-1 | Person_evidence | WBPerson105 | |||||
| WBPerson293 | |||||||||
| Sequence_name | F38B2.1 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | Cel IF A1 | Accession_evidence | EMBL | X70834 | |||||
| CelIF a1 | |||||||||
| A1 | Paper_evidence | WBPaper00006137 | |||||||
| CELE_F38B2.1 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ifa-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifa | ||||||||
| Allele | WBVar01186777 | ||||||||
| WBVar01186778 | |||||||||
| WBVar01186779 | |||||||||
| WBVar01499887 | |||||||||
| WBVar01186780 | |||||||||
| WBVar01690402 | |||||||||
| WBVar01186781 | |||||||||
| WBVar01499888 | |||||||||
| WBVar01186782 | |||||||||
| WBVar01186783 | |||||||||
| WBVar01186784 | |||||||||
| WBVar01186785 | |||||||||
| WBVar01186786 | |||||||||
| WBVar00092503 | |||||||||
| WBVar01186787 | |||||||||
| WBVar01499710 | |||||||||
| WBVar01186788 | |||||||||
| WBVar01186789 | |||||||||
| WBVar01186790 | |||||||||
| WBVar01186791 | |||||||||
| WBVar01186792 | |||||||||
| WBVar01186793 | |||||||||
| WBVar01186794 | |||||||||
| WBVar00083093 | |||||||||
| WBVar02009110 | |||||||||
| WBVar02009111 | |||||||||
| WBVar02083479 | |||||||||
| WBVar01496635 | |||||||||
| WBVar01620543 | |||||||||
| WBVar00067850 | |||||||||
| WBVar01620544 | |||||||||
| WBVar01620545 | |||||||||
| WBVar01620546 | |||||||||
| WBVar00067855 | |||||||||
| WBVar00067860 | |||||||||
| WBVar00517064 | |||||||||
| WBVar00517065 | |||||||||
| WBVar00517066 | |||||||||
| WBVar00517067 | |||||||||
| WBVar00517068 | |||||||||
| WBVar00517069 | |||||||||
| WBVar00517070 | |||||||||
| WBVar00517071 | |||||||||
| WBVar00517072 | |||||||||
| WBVar01759446 | |||||||||
| WBVar00275701 | |||||||||
| WBVar02152302 | |||||||||
| WBVar00257410 | |||||||||
| WBVar01782572 | |||||||||
| WBVar01186751 | |||||||||
| WBVar01186752 | |||||||||
| WBVar01186753 | |||||||||
| WBVar01186754 | |||||||||
| WBVar01186755 | |||||||||
| WBVar01186756 | |||||||||
| WBVar01186757 | |||||||||
| WBVar01186758 | |||||||||
| WBVar01186759 | |||||||||
| WBVar01186760 | |||||||||
| WBVar01186761 | |||||||||
| WBVar01186762 | |||||||||
| WBVar01186763 | |||||||||
| WBVar01186764 | |||||||||
| WBVar01186765 | |||||||||
| WBVar01186766 | |||||||||
| WBVar01186767 | |||||||||
| WBVar01186768 | |||||||||
| WBVar01186769 | |||||||||
| WBVar01186770 | |||||||||
| WBVar01186771 | |||||||||
| WBVar01186772 | |||||||||
| WBVar01186773 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01186774 | |||||||||
| WBVar01186775 | |||||||||
| WBVar01500067 | |||||||||
| WBVar01186776 | |||||||||
| Strain | WBStrain00036052 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (65) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum. | Paper_evidence | WBPaper00001981 | |||||
| WBPaper00004761 | |||||||||
| WBPaper00006137 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in intermediate filament. Expressed in several structures, including egg-laying apparatus; excretory cell; neurons; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | F38B2.1a | |||||||
| F38B2.1b | |||||||||
| F38B2.1c | |||||||||
| F38B2.1d | |||||||||
| F38B2.1e | |||||||||
| Corresponding_CDS_history | F38B2.1:wp83 | ||||||||
| Corresponding_transcript | F38B2.1a.1 | ||||||||
| F38B2.1b.1 | |||||||||
| F38B2.1c.1 | |||||||||
| F38B2.1d.1 | |||||||||
| F38B2.1e.1 | |||||||||
| Other_sequence (241) | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result (48) | ||||||||
| Expr_pattern | Expr1495 | ||||||||
| Expr2762 | |||||||||
| Expr1013956 | |||||||||
| Expr1031203 | |||||||||
| Expr1150559 | |||||||||
| Expr2012676 | |||||||||
| Expr2030912 | |||||||||
| Drives_construct | WBCnstr00010937 | ||||||||
| WBCnstr00036494 | |||||||||
| Construct_product | WBCnstr00010937 | ||||||||
| WBCnstr00036494 | |||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (212) | |||||||||
| Interaction (72) | |||||||||
| Map_info | Map | X | Position | 2.86537 | Error | 0.001386 | |||
| Positive | Positive_clone | F38B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4945 | |||||||
| 4421 | |||||||||
| 4442 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
