WormBase Tree Display for Gene: WBGene00001889

WBGene00001889 SMap: S_parent: Sequence: ZK131
  Identity: Version: 1
    Name: CGC_name: his-15 Person_evidence: WBPerson160
      Sequence_name: ZK131.9
      Molecular_name: ZK131.9
        ZK131.9.1
        CE07075
      Other_name: CELE_ZK131.9 Accession_evidence: NDB BX284602
      Public_name: his-15
    DB_info: Database: AceView gene 2O109
        WormFlux gene WBGene00001889
        NDB locus_tag CELE_ZK131.9
        NCBI gene 175026
        RefSeq protein NM_064487.1
        SwissProt UniProtAcc P04255
        UniProt_GCRP UniProtAcc P04255
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: his
    Allele: WBVar01499702
      WBVar01498435
      WBVar01498941
    Legacy_information: [C.elegansII] NMK. Histone type H2B. HIS3 cluster. [Roberts et al. 1989; EM]
    In_cluster: HIS3_cluster
    RNASeq_FPKM (74)
    GO_annotation: 00106123
      00109582
      00109583
      00109584
      00109585
    Ortholog (199)
    Paralog (16)
    Structured_description: Concise_description: his-15 encodes an H2B histone. Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC12 (H2B clustered histone 12); H2BC17 (H2B clustered histone 17); and H2BC3 (H2B clustered histone 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK131.9
    Corresponding_transcript: ZK131.9.1
    Other_sequence: MC00785
      MCC03885_1
      GO252435.1
      GO251777.1
    Associated_feature: WBsf222394
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr1162657
    Microarray_results (24)
    Expression_cluster: WBPaper00038061:aldicarb_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045401:N.parisii_40h_upregulated
      WBPaper00045401:N.parisii_64h_upregulated
      WBPaper00046303:P.aeruginosa_downregulated_protein
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046887:WNT-target
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:daf-2(e1370)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_upregulated
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00055013:HMG-4_interacting_protein
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056826:SGP_biased
      WBPaper00056900:ERH-2_interacting
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056900:TOST-1_interacting
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00057265:metaformin_downregulated_OP50
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00058942:henn-1(pk2295)_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059605:simr-1(cmp36)_downregulated
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062056:dpl-1(n2994)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00064201:SNA-1_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065392:Lb.delbrueckii_upregulated
      WBPaper00065392:Lb.gasseri_upregulated
      WBPaper00065392:Lb.reuteri_upregulated
      WBPaper00065392:P.pentosaceus_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00066232:ash-2(RNAi)_upregulated_WT
      cgc4386_cluster_1_1
      cgc4489_group_5
      cgc4489_group_22
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00028482:PA14_upregulated
      WBPaper00028789:PA14_vs_gacA_upregulated_8hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032948:FedUp
      WBPaper00034739:N2lessDR1350
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036383:ash-2_L3_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00042178:hlh-29(tm284)_upregulated
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044535:male_upregulated
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(83_min)
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:mixed_oogenesis-somatic
    SAGE_tag: SAGE:gctttggaggaaactcc Strand: Antisense
      SAGE:aactcttttg Strand: Sense
        Unambiguously_mapped
      SAGE:aactcttttgtcaacga Strand: Sense
        Unambiguously_mapped
      SAGE:acgtctcttctttccgt Strand: Antisense
      SAGE:acgtctcttc Strand: Antisense
    Interaction (207)
  Map_info: Map: II Position: 20.2996
    Positive: Positive_clone: ZK131 Inferred_automatically: From sequence, transcript, pseudogene data
        ZK831
    Pseudo_map_position
  Reference: WBPaper00001150
    WBPaper00005142
    WBPaper00005182
    WBPaper00038491
    WBPaper00055090
    WBPaper00057125
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene