WormBase Tree Display for Gene: WBGene00001824
expand all nodes | collapse all nodes | view schema
| WBGene00001824 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F13D11 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | hbl-1 | Person_evidence | WBPerson698 | |||||
| Sequence_name | F13D11.2 | ||||||||
| Molecular_name | F13D11.2a | ||||||||
| F13D11.2a.1 | |||||||||
| CE27956 | |||||||||
| F13D11.2b | |||||||||
| CE23646 | |||||||||
| F13D11.2b.1 | |||||||||
| Other_name | lin-57 | ||||||||
| CELE_F13D11.2 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | hbl-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00001824 | |||||
| WormFlux | gene | WBGene00001824 | |||||||
| NDB | locus_tag | CELE_F13D11.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001824|UniProtKB=Q9XYD3 | |||||||
| family | PTHR24392 | ||||||||
| NCBI | gene | 180848 | |||||||
| RefSeq | protein | NM_001047778.5 | |||||||
| NM_001047779.5 | |||||||||
| SwissProt | UniProtAcc | Q9XYD3 | |||||||
| TREEFAM | TREEFAM_ID | TF326588 | |||||||
| TrEMBL | UniProtAcc | Q27GU0 | |||||||
| UniProt_GCRP | UniProtAcc | Q9XYD3 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hbl | ||||||||
| Allele (73) | |||||||||
| Possibly_affected_by | WBVar02152888 | ||||||||
| Strain (11) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00016189 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00005009 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00003033 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00008762 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012385 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | hbl-1 encodes a C2H2-type zinc finger transcription factor related to Drosophila hunchback; hbl-1 is a heterochronic gene that plays an essential role in regulating developmental timing during postembryonic development; accordingly, mutations in hbl-1 affect locomotion, egg laying, body morphology, and hypodermal differentiation; hbl-1 is expressed in hypodermal precursor cells, neuronal precursor cells, and pharyngeal cells during embryogenesis and is primarily expressed in neurons during larval development; hbl-1 expression is negatively regulated by the let-7 miRNA whose expression is, in turn, negatively regulated by HBL-1 in a negative feedback loop. | Paper_evidence | WBPaper00003392 | |||||
| WBPaper00005908 | |||||||||
| WBPaper00005909 | |||||||||
| WBPaper00034754 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 20 Aug 2009 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and nematode larval development. Located in nucleus. Expressed in several structures, including body wall musculature; germ line; hypodermis; neurons; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F13D11.2a | |||||||
| F13D11.2b | |||||||||
| Corresponding_CDS_history | F13D11.2:wp155 | ||||||||
| Corresponding_transcript | F13D11.2a.1 | ||||||||
| F13D11.2b.1 | |||||||||
| Other_sequence | JI462622.1 | ||||||||
| JI164262.1 | |||||||||
| Oden_isotig23540 | |||||||||
| SC01112 | |||||||||
| JI164529.1 | |||||||||
| MI07402 | |||||||||
| MIC06569_1 | |||||||||
| GR977958.1 | |||||||||
| Associated_feature (43) | |||||||||
| Transcription_factor | WBTranscriptionFactor000175 | ||||||||
| Experimental_info | RNAi_result (78) | ||||||||
| Expr_pattern (15) | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product | WBCnstr00000374 | ||||||||
| WBCnstr00009982 | |||||||||
| WBCnstr00017352 | |||||||||
| WBCnstr00019440 | |||||||||
| WBCnstr00036665 | |||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (229) | |||||||||
| Interaction (217) | |||||||||
| Anatomy_function | WBbtf0427 | ||||||||
| WBProcess | WBbiopr:00000083 | ||||||||
| Map_info | Map | X | Position | -4.26909 | Error | 0.011372 | |||
| Positive | Positive_clone | F13D11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4396 | |||||||
| Pseudo_map_position | |||||||||
| Reference (125) | |||||||||
| Remark | Sequence connection from [Abrahante JE, Rougvie AE] | ||||||||
| old_name lin-57 becomes new_name hbl-1 from [Abrahante JE, Rougvie AE]. | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
