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WormBase Tree Display for Gene: WBGene00001824

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Name Class

WBGene00001824EvidenceCGC_data_submission
SMapS_parentSequenceF13D11
IdentityVersion1
NameCGC_namehbl-1Person_evidenceWBPerson698
Sequence_nameF13D11.2
Molecular_nameF13D11.2a
F13D11.2a.1
CE27956
F13D11.2b
CE23646
F13D11.2b.1
Other_namelin-57
CELE_F13D11.2Accession_evidenceNDBBX284606
Public_namehbl-1
DB_infoDatabaseWormQTLgeneWBGene00001824
WormFluxgeneWBGene00001824
NDBlocus_tagCELE_F13D11.2
PanthergeneCAEEL|WormBase=WBGene00001824|UniProtKB=Q9XYD3
familyPTHR24392
NCBIgene180848
RefSeqproteinNM_001047778.5
NM_001047779.5
SwissProtUniProtAccQ9XYD3
TREEFAMTREEFAM_IDTF326588
TrEMBLUniProtAccQ27GU0
UniProt_GCRPUniProtAccQ9XYD3
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhbl
AlleleWBVar02152888Inferred_automaticallyFrom strain object: VT3500
WBVar01830623
WBVar01487003
WBVar01150113
WBVar01880165
WBVar01150114
WBVar01880166
WBVar01150115
WBVar01880167
WBVar01880168
WBVar01150116
WBVar01150117
WBVar01150118
WBVar01150119
WBVar01150120
WBVar01150121
WBVar01150122
WBVar01150123
WBVar01150124
WBVar01150125
WBVar01150126
WBVar01150127
WBVar01150128
WBVar01150129
WBVar01150130
WBVar01150131
WBVar01150132
WBVar01150133
WBVar01150134
WBVar01150135
WBVar01150136
WBVar01150137
WBVar01150138
WBVar01150139
WBVar01550040
WBVar01150140
WBVar01150141
WBVar01150142
WBVar00142285
WBVar01150143
WBVar00504693
WBVar01150144
WBVar00504694
WBVar01150145
WBVar01150146
WBVar00504695
WBVar01150147
WBVar00504696
WBVar01150148
WBVar00249558
WBVar00504697
WBVar01150149
WBVar00504698
WBVar01150150
WBVar00504699
WBVar01150151
WBVar00504700
WBVar00504701
WBVar00504702
WBVar00504703
WBVar00088924
WBVar00079428
WBVar02064006
WBVar00079429
WBVar00079430
WBVar02064007
WBVar02064008
WBVar00252390
WBVar02139358
WBVar02139359
WBVar00275044
WBVar01815631
WBVar01500067
Possibly_affected_byWBVar02152888
Strain (11)
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (32)
ParalogWBGene00016189Caenorhabditis elegansFrom_analysisPanther
WBGene00005009Caenorhabditis elegansFrom_analysisPanther
WBGene00003033Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008762Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00012385Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionhbl-1 encodes a C2H2-type zinc finger transcription factor related to Drosophila hunchback; hbl-1 is a heterochronic gene that plays an essential role in regulating developmental timing during postembryonic development; accordingly, mutations in hbl-1 affect locomotion, egg laying, body morphology, and hypodermal differentiation; hbl-1 is expressed in hypodermal precursor cells, neuronal precursor cells, and pharyngeal cells during embryogenesis and is primarily expressed in neurons during larval development; hbl-1 expression is negatively regulated by the let-7 miRNA whose expression is, in turn, negatively regulated by HBL-1 in a negative feedback loop.Paper_evidenceWBPaper00003392
WBPaper00005908
WBPaper00005909
WBPaper00034754
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated20 Aug 2009 00:00:00
Automated_descriptionEnables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and nematode larval development. Located in nucleus. Expressed in several structures, including body wall musculature; germ line; hypodermis; neurons; and ventral nerve cord.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF13D11.2a
F13D11.2b
Corresponding_CDS_historyF13D11.2:wp155
Corresponding_transcriptF13D11.2a.1
F13D11.2b.1
Other_sequenceJI462622.1
JI164262.1
Oden_isotig23540
SC01112
JI164529.1
MI07402
MIC06569_1
GR977958.1
Associated_feature (43)
Transcription_factorWBTranscriptionFactor000175
Experimental_infoRNAi_result (78)
Expr_pattern (15)
Drives_construct (11)
Construct_productWBCnstr00000374
WBCnstr00009982
WBCnstr00017352
WBCnstr00019440
WBCnstr00036665
Microarray_results (27)
Expression_cluster (229)
Interaction (217)
Anatomy_functionWBbtf0427
WBProcessWBbiopr:00000083
Map_infoMapXPosition-4.26909Error0.011372
PositivePositive_cloneF13D11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4396
Pseudo_map_position
Reference (125)
RemarkSequence connection from [Abrahante JE, Rougvie AE]
old_name lin-57 becomes new_name hbl-1 from [Abrahante JE, Rougvie AE].
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene