WormBase Tree Display for Gene: WBGene00001694
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| WBGene00001694 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F41E6 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-5 | Person_evidence | WBPerson83 | |||||
| Sequence_name | F41E6.2 | ||||||||
| Molecular_name | F41E6.2 | ||||||||
| F41E6.2.1 | |||||||||
| CE10246 | |||||||||
| Other_name | F41E6 | Paper_evidence | WBPaper00002823 | ||||||
| CELE_F41E6.2 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | grd-5 | ||||||||
| DB_info | Database | AceView | gene | 5J99 | |||||
| WormQTL | gene | WBGene00001694 | |||||||
| WormFlux | gene | WBGene00001694 | |||||||
| NDB | locus_tag | CELE_F41E6.2 | |||||||
| NCBI | gene | 179244 | |||||||
| RefSeq | protein | NM_072822.6 | |||||||
| TrEMBL | UniProtAcc | O16462 | |||||||
| UniProt_GCRP | UniProtAcc | O16462 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (32) | |||||||||
| Strain | WBStrain00002346 | ||||||||
| WBStrain00051273 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00028098 | ||||||||
| 00028099 | |||||||||
| 00028100 | |||||||||
| 00028101 | |||||||||
| Ortholog (25) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | grd-5 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-5 is expressed in adultanterior and posterior seam cells, overlapping GRD-3 expression; theGround domain is predicted to form a cysteine-crosslinked proteininvolved in intercellular signalling, and it has subtle similarity tothe N-terminal Hedge domain of HEDGEHOG proteins; GRD-5 is weaklyrequired for normal molting; GRD-5 is also required for normal adultalae formation, growth to full size, and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||||
| WBPaper00003717 | |||||||||
| WBPaper00004651 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable signaling receptor binding activity. Involved in embryo development. Predicted to be located in extracellular region. Expressed in anterior arcade cell; pharyngeal neurons; rectal epithelium; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F41E6.2 | |||||||
| Corresponding_transcript | F41E6.2.1 | ||||||||
| Other_sequence (12) | |||||||||
| Associated_feature | WBsf647011 | ||||||||
| WBsf655105 | |||||||||
| WBsf661491 | |||||||||
| WBsf1000711 | |||||||||
| WBsf1000712 | |||||||||
| WBsf1000713 | |||||||||
| WBsf1020063 | |||||||||
| WBsf232135 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00014746 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000881 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077019 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032092 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076973 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076994 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046992 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1691 | ||||||||
| Expr636 | |||||||||
| Expr4431 | |||||||||
| Expr1011866 | |||||||||
| Expr1031011 | |||||||||
| Expr1150857 | |||||||||
| Expr2012235 | |||||||||
| Expr2030471 | |||||||||
| Drives_construct | WBCnstr00003015 | ||||||||
| WBCnstr00011994 | |||||||||
| WBCnstr00012460 | |||||||||
| WBCnstr00036762 | |||||||||
| Construct_product | WBCnstr00036762 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (276) | |||||||||
| Interaction (28) | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | V | Position | 1.49477 | Error | 0.004138 | |||
| Positive | Positive_clone | F41E6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002823 | ||||||||
| WBPaper00003717 | |||||||||
| WBPaper00011801 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00064105 | |||||||||
| Remark | grd-5 is paralogous to grd-10 | Paper_evidence | WBPaper00003717 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
