WormBase Tree Display for Gene: WBGene00001694
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WBGene00001694 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F41E6 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | grd-5 | Person_evidence | WBPerson83 | |||||
Sequence_name | F41E6.2 | ||||||||
Molecular_name | F41E6.2 | ||||||||
F41E6.2.1 | |||||||||
CE10246 | |||||||||
Other_name | F41E6 | Paper_evidence | WBPaper00002823 | ||||||
CELE_F41E6.2 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | grd-5 | ||||||||
DB_info | Database | AceView | gene | 5J99 | |||||
WormQTL | gene | WBGene00001694 | |||||||
WormFlux | gene | WBGene00001694 | |||||||
NDB | locus_tag | CELE_F41E6.2 | |||||||
NCBI | gene | 179244 | |||||||
RefSeq | protein | NM_072822.6 | |||||||
TrEMBL | UniProtAcc | O16462 | |||||||
UniProt_GCRP | UniProtAcc | O16462 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | grd | ||||||||
Allele (32) | |||||||||
Strain | WBStrain00002346 | ||||||||
WBStrain00051273 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00028098 | ||||||||
00028099 | |||||||||
00028100 | |||||||||
00028101 | |||||||||
Ortholog (25) | |||||||||
Paralog (24) | |||||||||
Structured_description | Concise_description | grd-5 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-5 is expressed in adultanterior and posterior seam cells, overlapping GRD-3 expression; theGround domain is predicted to form a cysteine-crosslinked proteininvolved in intercellular signalling, and it has subtle similarity tothe N-terminal Hedge domain of HEDGEHOG proteins; GRD-5 is weaklyrequired for normal molting; GRD-5 is also required for normal adultalae formation, growth to full size, and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||||
WBPaper00003717 | |||||||||
WBPaper00004651 | |||||||||
WBPaper00026841 | |||||||||
WBPaper00027263 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable signaling receptor binding activity. Involved in embryo development. Predicted to be located in extracellular region. Expressed in anterior arcade cell; pharyngeal neurons; rectal epithelium; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info (4) | |||||||||
Experimental_info | RNAi_result | WBRNAi00014746 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00000881 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00077019 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032092 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076973 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076994 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00046992 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram1691 | ||||||||
Expr636 | |||||||||
Expr4431 | |||||||||
Expr1011866 | |||||||||
Expr1031011 | |||||||||
Expr1150857 | |||||||||
Expr2012235 | |||||||||
Expr2030471 | |||||||||
Drives_construct | WBCnstr00003015 | ||||||||
WBCnstr00011994 | |||||||||
WBCnstr00012460 | |||||||||
WBCnstr00036762 | |||||||||
Construct_product | WBCnstr00036762 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (276) | |||||||||
Interaction (28) | |||||||||
WBProcess | WBbiopr:00000123 | ||||||||
Map_info | Map | V | Position | 1.49477 | Error | 0.004138 | |||
Positive | Positive_clone | F41E6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00002823 | ||||||||
WBPaper00003717 | |||||||||
WBPaper00011801 | |||||||||
WBPaper00026841 | |||||||||
WBPaper00028754 | |||||||||
WBPaper00031588 | |||||||||
WBPaper00064105 | |||||||||
Remark | grd-5 is paralogous to grd-10 | Paper_evidence | WBPaper00003717 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |