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WormBase Tree Display for Gene: WBGene00001444

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Name Class

WBGene00001444SMapS_parentSequenceF23B2
IdentityVersion1
NameCGC_nameflp-1Person_evidenceWBPerson369
Sequence_nameF23B2.5
Molecular_nameF23B2.5a
F23B2.5a.1
CE09585
F23B2.5b
CE32045
F23B2.5c
CE32046
F23B2.5b.1
F23B2.5c.1
Other_nameCELE_F23B2.5Accession_evidenceNDBBX284604
Public_nameflp-1
DB_infoDatabaseAceViewgene4J909
WormQTLgeneWBGene00001444
WormFluxgeneWBGene00001444
NDBlocus_tagCELE_F23B2.5
PanthergeneCAEEL|WormBase=WBGene00001444|UniProtKB=P41855
familyPTHR20986
NCBIgene177737
RefSeqproteinNM_182277.9
NM_182278.7
NM_069191.8
SwissProtUniProtAccP41855
TREEFAMTREEFAM_IDTF315840
UniProt_GCRPUniProtAccP41855
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classflp
LaboratoryNL
Reference_alleleWBVar00239184
Allele (27)
Legacy_information[C.elegansII] pk41 : Tc1 insertion, no known phenotype. Cloned: encodes FMRF-containing neuropeptides.Six exons, four encode FMRFamide-like peptides.Alternatively spliced transcripts. [Rosoff et al. 1992; NY]
[Nelson LS,] yn2 and yn4 are 1.4 kb and 2.1 kb deletion alleles derived from Tc1 insertion pk41. Both exhibit loopy uncoordinated movement, hyperactivity, defective in nose touch response (Not) and osmotic avoidance.
[Rosoff ML, Burglin TR, Li C] flp-1 is predicted gene F23B2.5
Strain (13)
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (14)
ParalogWBGene00001446Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001457Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001461Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionflp-1 can encode up to seven distinct, yet highly similar, FMRFamide-related peptides (FaRPs), small neuromodulatory peptides that are characterized by a C-terminal Arg-Phe-amide motif; in C. elegans, FLP-1 peptides are required for regulation of several behaviors, including well-coordinated, sinusoidal movement and the transition between active and inactive states of egg-laying; receptors for the FLP-1 peptides have not yet been identified, but genetic studies indicate that FLP-1 peptides may act through G-protein coupled receptors; flp-1 mRNAs are detected at all developmental stages, and a FLP-1 translational reporter fusion detects expression in the anteriorly positioned neurons AVK, AVA, AVE, RIG, RMG, AIY, AIA, and M5Paper_evidenceWBPaper00003158
WBPaper00003193
WBPaper00003951
Curator_confirmedWBPerson1843
Date_last_updated28 Nov 2005 00:00:00
Automated_descriptionEnables neuropeptide receptor binding activity. Involved in several processes, including mechanosensory behavior; regulation of egg-laying behavior; and response to serotonin. Predicted to be located in extracellular region. Expressed in RIG; nerve ring; and neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF23B2.5a
F23B2.5b
F23B2.5c
Corresponding_CDS_historyF23B2.5:wp87
Corresponding_transcriptF23B2.5a.1
F23B2.5b.1
F23B2.5c.1
Other_sequence (47)
Associated_featureWBsf646216
WBsf646217
WBsf228791
Experimental_infoRNAi_result (12)
Expr_pattern (14)
Drives_constructWBCnstr00000169
WBCnstr00001431
WBCnstr00010262
WBCnstr00011075
WBCnstr00013010
WBCnstr00016921
WBCnstr00016925
WBCnstr00020021
WBCnstr00020696
WBCnstr00036943
Construct_productWBCnstr00005113
WBCnstr00010262
WBCnstr00011561
WBCnstr00036943
AntibodyWBAntibody00000611
Microarray_results (33)
Expression_cluster (183)
Interaction (58)
Anatomy_functionWBbtf0039
Map_infoMapIVPosition4.05525Error0.003447
Well_ordered
PositivePositive_cloneF23B2Person_evidenceWBPerson83
WBPerson369
WBPerson6130
WBPerson6131
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point3737
4892
ReferenceWBPaper00001561
WBPaper00001716
WBPaper00001984
WBPaper00002006
WBPaper00002356
WBPaper00002563
WBPaper00002708
WBPaper00002755
WBPaper00003158
WBPaper00003193
WBPaper00003889
WBPaper00003915
WBPaper00003941
WBPaper00003951
WBPaper00004257
WBPaper00004310
WBPaper00004931
WBPaper00006011
WBPaper00006103
WBPaper00010101
WBPaper00010284
WBPaper00010426
WBPaper00010457
WBPaper00010476
WBPaper00010565
WBPaper00010797
WBPaper00010904
WBPaper00011086
WBPaper00011098
WBPaper00011270
WBPaper00011699
WBPaper00012130
WBPaper00013186
WBPaper00014754
WBPaper00015745
WBPaper00016740
WBPaper00016919
WBPaper00017677
WBPaper00018025
WBPaper00018300
WBPaper00019234
WBPaper00021967
WBPaper00022056
WBPaper00022585
WBPaper00022586
WBPaper00023025
WBPaper00023165
WBPaper00023309
WBPaper00023788
WBPaper00024196
WBPaper00024457
WBPaper00026655
WBPaper00026738
WBPaper00026828
WBPaper00026832
WBPaper00026994
WBPaper00027003
WBPaper00027242
WBPaper00027407
WBPaper00027661
WBPaper00028134
WBPaper00028157
WBPaper00028453
WBPaper00029185
WBPaper00030763
WBPaper00031602
WBPaper00041132
WBPaper00042376
WBPaper00043437
WBPaper00043484
WBPaper00043908
WBPaper00046333
WBPaper00049648
WBPaper00053388
WBPaper00053509
WBPaper00055565
WBPaper00055865
WBPaper00058558
WBPaper00059441
WBPaper00061309
WBPaper00061375
WBPaper00063684
WBPaper00063818
WBPaper00063846
WBPaper00064233
WBPaper00064665
WBPaper00064754
WBPaper00064927
WBPaper00065273
WBPaper00065340
WBPaper00065946
WBPaper00065948
RemarkData extracted from Nelson et al. (1998)
MethodGene