WormBase Tree Display for Gene: WBGene00001444
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| WBGene00001444 | SMap | S_parent | Sequence | F23B2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | flp-1 | Person_evidence | WBPerson369 | |||||
| Sequence_name | F23B2.5 | ||||||||
| Molecular_name | F23B2.5a | ||||||||
| F23B2.5a.1 | |||||||||
| CE09585 | |||||||||
| F23B2.5b | |||||||||
| CE32045 | |||||||||
| F23B2.5c | |||||||||
| CE32046 | |||||||||
| F23B2.5b.1 | |||||||||
| F23B2.5c.1 | |||||||||
| Other_name | CELE_F23B2.5 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | flp-1 | ||||||||
| DB_info | Database | AceView | gene | 4J909 | |||||
| WormQTL | gene | WBGene00001444 | |||||||
| WormFlux | gene | WBGene00001444 | |||||||
| NDB | locus_tag | CELE_F23B2.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001444|UniProtKB=P41855 | |||||||
| family | PTHR20986 | ||||||||
| NCBI | gene | 177737 | |||||||
| RefSeq | protein | NM_182277.9 | |||||||
| NM_182278.7 | |||||||||
| NM_069191.8 | |||||||||
| SwissProt | UniProtAcc | P41855 | |||||||
| TREEFAM | TREEFAM_ID | TF315840 | |||||||
| UniProt_GCRP | UniProtAcc | P41855 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | flp | ||||||||
| Laboratory | NL | ||||||||
| Reference_allele | WBVar00239184 | ||||||||
| Allele (27) | |||||||||
| Legacy_information | [C.elegansII] pk41 : Tc1 insertion, no known phenotype. Cloned: encodes FMRF-containing neuropeptides.Six exons, four encode FMRFamide-like peptides.Alternatively spliced transcripts. [Rosoff et al. 1992; NY] | ||||||||
| [Nelson LS,] yn2 and yn4 are 1.4 kb and 2.1 kb deletion alleles derived from Tc1 insertion pk41. Both exhibit loopy uncoordinated movement, hyperactivity, defective in nose touch response (Not) and osmotic avoidance. | |||||||||
| [Rosoff ML, Burglin TR, Li C] flp-1 is predicted gene F23B2.5 | |||||||||
| Strain (13) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (14) | |||||||||
| Paralog | WBGene00001446 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00001457 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001461 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | flp-1 can encode up to seven distinct, yet highly similar, FMRFamide-related peptides (FaRPs), small neuromodulatory peptides that are characterized by a C-terminal Arg-Phe-amide motif; in C. elegans, FLP-1 peptides are required for regulation of several behaviors, including well-coordinated, sinusoidal movement and the transition between active and inactive states of egg-laying; receptors for the FLP-1 peptides have not yet been identified, but genetic studies indicate that FLP-1 peptides may act through G-protein coupled receptors; flp-1 mRNAs are detected at all developmental stages, and a FLP-1 translational reporter fusion detects expression in the anteriorly positioned neurons AVK, AVA, AVE, RIG, RMG, AIY, AIA, and M5 | Paper_evidence | WBPaper00003158 | |||||
| WBPaper00003193 | |||||||||
| WBPaper00003951 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 28 Nov 2005 00:00:00 | ||||||||
| Automated_description | Enables neuropeptide receptor binding activity. Involved in several processes, including mechanosensory behavior; regulation of egg-laying behavior; and response to serotonin. Predicted to be located in extracellular region. Expressed in RIG; nerve ring; and neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F23B2.5a | |||||||
| F23B2.5b | |||||||||
| F23B2.5c | |||||||||
| Corresponding_CDS_history | F23B2.5:wp87 | ||||||||
| Corresponding_transcript | F23B2.5a.1 | ||||||||
| F23B2.5b.1 | |||||||||
| F23B2.5c.1 | |||||||||
| Other_sequence (47) | |||||||||
| Associated_feature | WBsf646216 | ||||||||
| WBsf646217 | |||||||||
| WBsf228791 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00000169 | ||||||||
| WBCnstr00001431 | |||||||||
| WBCnstr00010262 | |||||||||
| WBCnstr00011075 | |||||||||
| WBCnstr00013010 | |||||||||
| WBCnstr00016921 | |||||||||
| WBCnstr00016925 | |||||||||
| WBCnstr00020021 | |||||||||
| WBCnstr00020696 | |||||||||
| WBCnstr00036943 | |||||||||
| Construct_product | WBCnstr00005113 | ||||||||
| WBCnstr00010262 | |||||||||
| WBCnstr00011561 | |||||||||
| WBCnstr00036943 | |||||||||
| Antibody | WBAntibody00000611 | ||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (183) | |||||||||
| Interaction (58) | |||||||||
| Anatomy_function | WBbtf0039 | ||||||||
| Map_info | Map | IV | Position | 4.05525 | Error | 0.003447 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F23B2 | Person_evidence | WBPerson83 | |||||
| WBPerson369 | |||||||||
| WBPerson6130 | |||||||||
| WBPerson6131 | |||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 3737 | |||||||
| 4892 | |||||||||
| Reference (92) | |||||||||
| Remark | Data extracted from Nelson et al. (1998) | ||||||||
| Method | Gene |
