WormBase Tree Display for Gene: WBGene00001398
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| WBGene00001398 | SMap | S_parent | Sequence | VZK822L | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | fat-6 | |||||||
| Sequence_name | VZK822L.1 | ||||||||
| Molecular_name | VZK822L.1a | ||||||||
| VZK822L.1a.1 | |||||||||
| CE18302 | |||||||||
| VZK822L.1b | |||||||||
| CE44710 | |||||||||
| VZK822L.1c | |||||||||
| CE44565 | |||||||||
| VZK822L.1b.1 | |||||||||
| VZK822L.1c.1 | |||||||||
| Other_name | CELE_VZK822L.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | fat-6 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fat | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00004014 | ||||||||
| WBStrain00004016 | |||||||||
| WBStrain00004021 | |||||||||
| WBStrain00008409 | |||||||||
| WBStrain00030677 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (59) | |||||||||
| Paralog | WBGene00001397 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001399 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | fat-6 encodes an Acyl-CoA desaturase (also known as delta-9 fatty acid desaturase); when expressed heterologously in S. cerevisiae, FAT-6 rescues the fatty acid auxotrophy of the ole1 delta-9 desaturase mutant; FAT-6 readily desaturates stearic acid (18:0), or similar fatty acids (17:0 or 18:1 delta-11 trans), but shows less activity on palmitic acid (16:0), and no activity on other medium chain fatty acids (14:0 or 15:0); based on similarity to mammalian Acyl-CoA desaturases, FAT-6 is predicted to localize to the endoplasmic reticulum membrane. | Paper_evidence | WBPaper00004149 | |||||
| WBPaper00013538 | |||||||||
| WBPaper00013550 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 16 May 2014 00:00:00 | ||||||||
| Automated_description | Enables stearoyl-CoA 9-desaturase activity. Involved in innate immune response; long-chain fatty acid biosynthetic process; and post-embryonic development. Predicted to be located in endoplasmic reticulum membrane. Expressed in hypodermis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112160 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:21088) | ||||
| Molecular_info | Corresponding_CDS | VZK822L.1a | |||||||
| VZK822L.1b | |||||||||
| VZK822L.1c | |||||||||
| Corresponding_transcript | VZK822L.1a.1 | ||||||||
| VZK822L.1b.1 | |||||||||
| VZK822L.1c.1 | |||||||||
| Other_sequence (71) | |||||||||
| Associated_feature | WBsf652264 | ||||||||
| WBsf979000 | |||||||||
| WBsf981829 | |||||||||
| WBsf230930 | |||||||||
| WBsf230931 | |||||||||
| Experimental_info | RNAi_result (38) | ||||||||
| Expr_pattern | Expr4291 | ||||||||
| Expr4573 | |||||||||
| Expr1030837 | |||||||||
| Expr1158028 | |||||||||
| Expr2011439 | |||||||||
| Expr2029677 | |||||||||
| Drives_construct | WBCnstr00011889 | ||||||||
| WBCnstr00036972 | |||||||||
| Construct_product | WBCnstr00011889 | ||||||||
| WBCnstr00016672 | |||||||||
| WBCnstr00036972 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (261) | |||||||||
| Interaction (309) | |||||||||
| WBProcess | WBbiopr:00000121 | ||||||||
| Map_info | Map | IV | Position | 5.39558 | Error | 0.007351 | |||
| Positive | Positive_clone | VZK822l | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4302 | |||||||
| 4854 | |||||||||
| 4821 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (108) | |||||||||
| Picture | WBPicture0000013088 | ||||||||
| WBPicture0000013096 | |||||||||
| WBPicture0000013098 | |||||||||
| Remark | sequence connection from J.Watts | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
