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WormBase Tree Display for Gene: WBGene00001324

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Name Class

WBGene00001324SMapS_parentSequenceR11E3
IdentityVersion1
NameCGC_nameeor-1Person_evidenceWBPerson637
Sequence_nameR11E3.6
Molecular_nameR11E3.6a
R11E3.6a.1
CE19548
R11E3.6b
CE48689
R11E3.6b.1
Other_nameCELE_R11E3.6Accession_evidenceNDBBX284604
Public_nameeor-1
DB_infoDatabaseAceViewgene4F558
WormQTLgeneWBGene00001324
SignaLinkproteinWBGene00001324
WormFluxgeneWBGene00001324
NDBlocus_tagCELE_R11E3.6
PanthergeneCAEEL|WormBase=WBGene00001324|UniProtKB=G5EDU4
familyPTHR24388
NCBIgene177249
RefSeqproteinNM_001380208.1
NM_001380207.3
TrEMBLUniProtAccU4PEC2
G5EDU4
UniProt_GCRPUniProtAccG5EDU4
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classeor
Allele (100)
StrainWBStrain00031868
WBStrain00035410
RNASeq_FPKM (74)
GO_annotation (21)
Contained_in_operonCEOP4152
Ortholog (43)
ParalogWBGene00045068Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
WBGene00012405Caenorhabditis elegansFrom_analysisPanther
WBGene00021387Caenorhabditis elegansFrom_analysisPanther
WBGene00018959Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021374Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioneor-1 encodes an ortholog of the human BTB/zinc-finger transcription factor PLZF (OMIM:176797), which is is found as a retinoic acid receptor alpha (RARA) fusion in acute promyelocytic leukemia (APL); EOR-1 positively regulates RAS/RAF-mediated signalling during excretory system development, as well as RAS/RAF- and WNT-mediated signalling during P12 fate specification; EOR-1 may function with EOR-2 and Hox genes to control the expression of Ras- and Wnt-responsive genes.Paper_evidenceWBPaper00005068
WBPaper00005250
WBPaper00005344
WBPaper00005412
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; nematode male tail tip morphogenesis; and signal transduction. Located in nucleus. Expressed in several structures, including dorsal nerve cord; gonad; pharynx; and vulval precursor cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR11E3.6a
R11E3.6b
Corresponding_transcriptR11E3.6a.1
R11E3.6b.1
Other_sequence (26)
Associated_featureWBsf651781
WBsf667915
WBsf667916
WBsf667917
WBsf978704
WBsf996396
WBsf1017314
WBsf230018
Gene_product_binds (11290)
Transcription_factorWBTranscriptionFactor000003
Experimental_infoRNAi_resultWBRNAi00051792Inferred_automaticallyRNAi_primary
WBRNAi00034860Inferred_automaticallyRNAi_primary
WBRNAi00022781Inferred_automaticallyRNAi_primary
WBRNAi00061867Inferred_automaticallyRNAi_primary
WBRNAi00022780Inferred_automaticallyRNAi_primary
Expr_pattern (15)
Drives_construct (12)
Construct_product (14)
AntibodyWBAntibody00002078
Microarray_results (21)
Expression_cluster (102)
Interaction (168)
Map_infoMapIVPosition1.25427Error0.010263
PositivePositive_cloneR11E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4038
4954
Pos_neg_data10661
Reference (55)
RemarkSequence connection from [Sundaram M]. krb 14/11/01
Positive_clone, Description and Alleles(cs28, cs40, cs44) data extracted from [Rocheleau CE, Howard RM, Goldman AP, Volk ML, Girard LJ,Sundaram MV] [ck1 020828]
MethodGene