WormBase Tree Display for Gene: WBGene00001165
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| WBGene00001165 | SMap | S_parent | Sequence | F56A11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | efn-4 | Person_evidence | WBPerson893 | |||||
| Sequence_name | F56A11.3 | ||||||||
| Molecular_name | F56A11.3 | ||||||||
| F56A11.3.1 | |||||||||
| CE29503 | |||||||||
| Other_name | mab-26 | ||||||||
| CELE_F56A11.3 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | efn-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | efn | ||||||||
| Allele (170) | |||||||||
| Legacy_information | [C.elegansII] bx80sd : fusions among all rays; also head, body and (especially) tail deformities; bx80/+ impenetrant R4 to R3 transformation. [Chow and Emmons 1994; EM] | ||||||||
| Strain | WBStrain00005372 | ||||||||
| WBStrain00007176 | |||||||||
| WBStrain00049265 | |||||||||
| WBStrain00049276 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (33) | |||||||||
| Ortholog (50) | |||||||||
| Paralog | WBGene00001163 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001164 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00006869 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | efn-4 encodes a divergent member of the ephrin family of ligands; efn-4 is required for neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; EFN-4 can interact weakly with VAB-1 in vitro; EFN-4 is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure. | Paper_evidence | WBPaper00003865 | |||||
| WBPaper00005631 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 23 Jul 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable ephrin receptor binding activity. Involved in several processes, including embryonic morphogenesis; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in axon and neuronal cell body. Expressed in several structures, including CAN; epithelial cell; ganglia; intestinal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1934 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||||
| DOID:14737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||||
| Molecular_info | Corresponding_CDS | F56A11.3 | |||||||
| Corresponding_transcript | F56A11.3.1 | ||||||||
| Other_sequence | CR11929 | ||||||||
| TS00903 | |||||||||
| TSC03402_1 | |||||||||
| CRC05251_1 | |||||||||
| CBC06448_1 | |||||||||
| CR02130 | |||||||||
| Associated_feature (22) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00111800 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00067312 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086136 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067361 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00064650 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048574 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015760 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00000722 | ||||||||
| WBCnstr00000723 | |||||||||
| WBCnstr00006419 | |||||||||
| WBCnstr00011024 | |||||||||
| WBCnstr00037053 | |||||||||
| WBCnstr00042431 | |||||||||
| WBCnstr00042437 | |||||||||
| Construct_product | WBCnstr00006419 | ||||||||
| WBCnstr00021468 | |||||||||
| WBCnstr00021469 | |||||||||
| WBCnstr00021470 | |||||||||
| WBCnstr00021472 | |||||||||
| WBCnstr00021473 | |||||||||
| WBCnstr00021477 | |||||||||
| WBCnstr00022268 | |||||||||
| WBCnstr00037053 | |||||||||
| Antibody | WBAntibody00000596 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (158) | |||||||||
| Interaction (63) | |||||||||
| WBProcess | WBbiopr:00000025 | ||||||||
| Map_info | Map | IV | Position | -25.7615 | Error | 0.138637 | |||
| Positive | Positive_clone | F56A11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 3132 | |||||||
| 4992 | |||||||||
| 5641 | |||||||||
| Reference (44) | |||||||||
| Method | Gene |
