WormBase Tree Display for Gene: WBGene00001164
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| WBGene00001164 | SMap | S_parent | Sequence | F15A2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | efn-3 | Person_evidence | WBPerson893 | |||||
| Sequence_name | F15A2.5 | ||||||||
| Molecular_name | F15A2.5 | ||||||||
| F15A2.5.1 | |||||||||
| CE44529 | |||||||||
| Other_name | CELE_F15A2.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | efn-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | efn | ||||||||
| Allele (35) | |||||||||
| Strain | WBStrain00029134 | ||||||||
| WBStrain00005372 | |||||||||
| WBStrain00005375 | |||||||||
| WBStrain00005671 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00064874 | ||||||||
| 00064875 | |||||||||
| 00064876 | |||||||||
| 00064877 | |||||||||
| 00064878 | |||||||||
| 00108359 | |||||||||
| Ortholog (28) | |||||||||
| Paralog | WBGene00001163 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006869 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001165 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | efn-3 encodes a potential GPI-modified ephrin that is, with EFN-2, is required for normal epidermal organization in the male tail; EFN-3, along with EFN-1 and EFN-2, activates the VAB-1 tyrosine kinase in vivo and binds it in vitro, and has a minor role in embryonic epiboly. | Paper_evidence | WBPaper00003865 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable ephrin receptor binding activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1934 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||||
| DOID:14737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||||
| Molecular_info | Corresponding_CDS | F15A2.5 | |||||||
| Corresponding_CDS_history | F15A2.5:wp109 | ||||||||
| F15A2.5:wp211 | |||||||||
| Corresponding_transcript | F15A2.5.1 | ||||||||
| Associated_feature | WBsf1007619 | ||||||||
| WBsf1024237 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00044670 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00068189 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00068216 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067728 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00064787 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013336 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030979 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067850 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1011959 | ||||||||
| Expr1148644 | |||||||||
| Drives_construct | WBCnstr00037054 | ||||||||
| Construct_product | WBCnstr00009795 | ||||||||
| WBCnstr00009796 | |||||||||
| WBCnstr00037054 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (145) | |||||||||
| Interaction (72) | |||||||||
| Map_info | Map | X | Position | 12.6185 | Error | 0.012221 | |||
| Positive | Positive_clone | F15A2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4276 | |||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Sequence connection from [Wang X, Culotti JG, Pawson T] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
