WormBase Tree Display for Gene: WBGene00001025
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| WBGene00001025 | SMap | S_parent | Sequence | C55B6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dnj-7 | Person_evidence | WBPerson625 | |||||
| Sequence_name | C55B6.2 | ||||||||
| Molecular_name | C55B6.2 | ||||||||
| C55B6.2.1 | |||||||||
| CE09008 | |||||||||
| Other_name | CELE_C55B6.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | dnj-7 | ||||||||
| DB_info | Database | AceView | gene | XH815 | |||||
| WormQTL | gene | WBGene00001025 | |||||||
| WormFlux | gene | WBGene00001025 | |||||||
| NDB | locus_tag | CELE_C55B6.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001025|UniProtKB=P91189 | |||||||
| family | PTHR24074 | ||||||||
| NCBI | gene | 180983 | |||||||
| RefSeq | protein | NM_076808.7 | |||||||
| TREEFAM | TREEFAM_ID | TF105162 | |||||||
| TrEMBL | UniProtAcc | P91189 | |||||||
| UniProt_GCRP | UniProtAcc | P91189 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dnj | ||||||||
| Allele (69) | |||||||||
| Strain | WBStrain00001214 | ||||||||
| WBStrain00036236 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00050221 | ||||||||
| 00050222 | |||||||||
| 00050223 | |||||||||
| 00050224 | |||||||||
| 00050225 | |||||||||
| 00050226 | |||||||||
| 00050227 | |||||||||
| 00105805 | |||||||||
| 00105815 | |||||||||
| Contained_in_operon | CEOPX167 | ||||||||
| Ortholog (39) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | dnj-7 encodes a protein containing a DnaJ domain that is orthologous to vertebrate P58IPK/DNAJC3, peripheral membrane proteins of the rough endoplasmic reticulum (ER) that function in co-translocational ER protein degradation during ER stress; in C. elegans, loss of dnj-7 activity via RNAi results in increased expression of an hsp-4::gfp (BiP) stress-inducible reporter fusion, suggesting that dnj-7 functions to regulate ER homeostasis. | Paper_evidence | WBPaper00012768 | |||||
| WBPaper00012859 | |||||||||
| WBPaper00025202 | |||||||||
| WBPaper00032192 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 01 Oct 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable misfolded protein binding activity; protein kinase inhibitor activity; and protein-folding chaperone binding activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen. Expressed in head. Is an ortholog of human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C55B6.2 | |||||||
| Corresponding_transcript | C55B6.2.1 | ||||||||
| Other_sequence (29) | |||||||||
| Associated_feature | WBsf648282 | ||||||||
| WBsf1005757 | |||||||||
| WBsf235904 | |||||||||
| WBsf235905 | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Chronogram2050 | ||||||||
| Expr5591 | |||||||||
| Expr1021713 | |||||||||
| Expr1030637 | |||||||||
| Expr1147199 | |||||||||
| Expr2011010 | |||||||||
| Expr2029248 | |||||||||
| Drives_construct | WBCnstr00002107 | ||||||||
| WBCnstr00037135 | |||||||||
| Construct_product | WBCnstr00037135 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (144) | |||||||||
| Interaction (37) | |||||||||
| WBProcess | WBbiopr:00000046 | ||||||||
| WBbiopr:00000079 | |||||||||
| Map_info | Map | X | Position | -1.79986 | Error | 0.003872 | |||
| Positive | Positive_clone | C55B6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5572 | |||||||
| 5612 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005432 | ||||||||
| WBPaper00025202 | |||||||||
| WBPaper00031857 | |||||||||
| WBPaper00032192 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062289 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
