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WormBase Tree Display for Gene: WBGene00000961

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Name Class

WBGene00000961SMapS_parentSequenceT21B6
IdentityVersion1
NameCGC_namedgn-1Person_evidenceWBPerson345
Sequence_nameT21B6.1
Molecular_nameT21B6.1
T21B6.1.1
CE03679
T21B6.1.2
Other_nameCELE_T21B6.1Accession_evidenceNDBBX284606
Public_namedgn-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdgn
Allele (109)
Possibly_affected_byWBVar02152924
StrainWBStrain00005032
WBStrain00005038
WBStrain00005039
WBStrain00047387
WBStrain00053443
RNASeq_FPKM (74)
GO_annotation (26)
Ortholog (31)
ParalogWBGene00018943Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptiondgn-1 encodes dystroglycan, a basement membrane component.Paper_evidenceWBPaper00027321
Curator_confirmedWBPerson1843
Date_last_updated26 Jan 2012 00:00:00
Automated_descriptionPredicted to enable laminin binding activity. Involved in anatomical structure morphogenesis; inductive cell migration; and positive regulation of locomotion. Located in basal plasma membrane. Expressed in several structures, including ALM; PVP; e2; gonad; and lumbar ganglion. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; Fukuyama congenital muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2D; autosomal recessive limb-girdle muscular dystrophy type 2P; bronchopulmonary dysplasia; congenital muscular dystrophy-dystroglycanopathy type A9; and inclusion body myositis. Is an ortholog of human DAG1 (dystroglycan 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110278Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:0050559Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:11723Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:3429Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:0110293Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:11650Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:0111232Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
Molecular_infoCorresponding_CDST21B6.1
Corresponding_transcriptT21B6.1.1
T21B6.1.2
Other_sequence (16)
Associated_feature (19)
Experimental_infoRNAi_resultWBRNAi00035744Inferred_automaticallyRNAi_primary
WBRNAi00018957Inferred_automaticallyRNAi_primary
WBRNAi00110305Inferred_automaticallyRNAi_primary
WBRNAi00053703Inferred_automaticallyRNAi_primary
WBRNAi00092897Inferred_automaticallyRNAi_primary
Expr_patternExpr4218
Expr4219
Expr9931
Expr12559
Expr14845
Expr1022924
Expr1030596
Expr1157255
Expr2010868
Expr2029106
Drives_constructWBCnstr00011834
WBCnstr00014941
WBCnstr00015884
WBCnstr00037177
WBCnstr00038162
Construct_productWBCnstr00011834
WBCnstr00015884
WBCnstr00016598
WBCnstr00037177
WBCnstr00038162
AntibodyWBAntibody00001077
WBAntibody00001078
Microarray_results (28)
Expression_cluster (171)
Interaction (32)
Map_infoMapXPosition2.70681Error0.005584
PositivePositive_cloneT21B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (23)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene