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WormBase Tree Display for Gene: WBGene00000788

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Name Class

WBGene00000788EvidencePaper_evidenceWBPaper00004821
SMapS_parentSequenceF32B5
IdentityVersion1
NameCGC_namecpz-1
Sequence_nameF32B5.8
Molecular_nameF32B5.8a
F32B5.8a.1
CE36646
F32B5.8b
CE50019
F32B5.8b.1
Other_nameCELE_F32B5.8Accession_evidenceNDBBX284601
Public_namecpz-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpz
Allele (65)
StrainWBStrain00031453
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (34)
Paralog (28)
Structured_descriptionConcise_descriptioncpz-1 encodes a homolog of cathepsin z-like cysteine protease cyclicallyexpressed in hypodermal cells throughout development (along with adultgonad and pharynx) and required for normal molting; CPZ-1 protein ispresent in cuticle regions shortly before their degradation duringecydsis, and this expression pattern is conserved in Onchocerca volvulus;cpz-1(ok497) and cpz-1(RNAi) worms have defective molting, along withmisshapen heads and tails, defective gonads, and embryonic lethality.Paper_evidenceWBPaper00006379
Curator_confirmedWBPerson567
Date_last_updated21 Aug 2006 00:00:00
Automated_descriptionPredicted to enable cysteine-type endopeptidase activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; gonad morphogenesis; and post-embryonic development. Located in collagen and cuticulin-based cuticle extracellular matrix; extracellular space; and yolk granule. Expressed in several structures, including anterior hypodermis; cuticle; intestine; pharynx; and vulva. Is an ortholog of human CTSZ (cathepsin Z).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF32B5.8a
F32B5.8b
Corresponding_CDS_historyF32B5.8:wp123
Corresponding_transcriptF32B5.8a.1
F32B5.8b.1
Other_sequence (237)
Associated_featureWBsf648984
WBsf717464
WBsf980972
WBsf982941
WBsf1009378
WBsf219056
Experimental_infoRNAi_result (12)
Expr_patternExpr2400
Expr2892
Expr2893
Expr7868
Expr1014352
Expr1030489
Expr1149993
Expr2010522
Expr2028762
Drives_constructWBCnstr00010810
WBCnstr00011010
WBCnstr00019867
WBCnstr00037275
Construct_productWBCnstr00037275
AntibodyWBAntibody00000710
Microarray_results (18)
Expression_cluster (228)
Interaction (23)
Map_infoMapIPosition-7.97279Error0.169868
PositivePositive_cloneF32B5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4238
5249
Pseudo_map_position
ReferenceWBPaper00006379
WBPaper00010400
WBPaper00027761
WBPaper00038491
WBPaper00055090
WBPaper00059755
WBPaper00062444
WBPaper00064339
WBPaper00065026
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
Homolog of Ov-cpz-1Paper_evidenceWBPaper00004821
MethodGene