WormBase Tree Display for Gene: WBGene00000788
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WBGene00000788 | Evidence | Paper_evidence | WBPaper00004821 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F32B5 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cpz | ||||||
Allele (65) | |||||||
Strain | WBStrain00031453 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (19) | |||||||
Ortholog (34) | |||||||
Paralog (28) | |||||||
Structured_description | Concise_description | cpz-1 encodes a homolog of cathepsin z-like cysteine protease cyclicallyexpressed in hypodermal cells throughout development (along with adultgonad and pharynx) and required for normal molting; CPZ-1 protein ispresent in cuticle regions shortly before their degradation duringecydsis, and this expression pattern is conserved in Onchocerca volvulus;cpz-1(ok497) and cpz-1(RNAi) worms have defective molting, along withmisshapen heads and tails, defective gonads, and embryonic lethality. | Paper_evidence | WBPaper00006379 | |||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 21 Aug 2006 00:00:00 | ||||||
Automated_description | Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; gonad morphogenesis; and post-embryonic development. Located in collagen and cuticulin-based cuticle extracellular matrix; extracellular space; and yolk granule. Expressed in several structures, including anterior hypodermis; cuticle; intestine; pharynx; and vulva. Is an ortholog of human CTSZ (cathepsin Z). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F32B5.8a | |||||
F32B5.8b | |||||||
Corresponding_CDS_history | F32B5.8:wp123 | ||||||
Corresponding_transcript | F32B5.8a.1 | ||||||
F32B5.8b.1 | |||||||
Other_sequence (237) | |||||||
Associated_feature | WBsf648984 | ||||||
WBsf717464 | |||||||
WBsf980972 | |||||||
WBsf982941 | |||||||
WBsf1009378 | |||||||
WBsf219056 | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern | Expr2400 | ||||||
Expr2892 | |||||||
Expr2893 | |||||||
Expr7868 | |||||||
Expr1014352 | |||||||
Expr1030489 | |||||||
Expr1149993 | |||||||
Expr2010522 | |||||||
Expr2028762 | |||||||
Drives_construct | WBCnstr00010810 | ||||||
WBCnstr00011010 | |||||||
WBCnstr00019867 | |||||||
WBCnstr00037275 | |||||||
Construct_product | WBCnstr00037275 | ||||||
Antibody | WBAntibody00000710 | ||||||
Microarray_results (18) | |||||||
Expression_cluster (228) | |||||||
Interaction (23) | |||||||
Map_info | Map | I | Position | -7.97279 | Error | 0.169868 | |
Positive | Positive_clone | F32B5 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4238 | |||||
5249 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00006379 | ||||||
WBPaper00010400 | |||||||
WBPaper00027761 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00059755 | |||||||
WBPaper00062444 | |||||||
WBPaper00064339 | |||||||
WBPaper00065026 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Homolog of Ov-cpz-1 | Paper_evidence | WBPaper00004821 | |||||
Method | Gene |