WormBase Tree Display for Gene: WBGene00000788
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WBGene00000788 | Evidence | Paper_evidence | WBPaper00004821 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F32B5 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | cpz-1 | |||||||
Sequence_name | F32B5.8 | ||||||||
Molecular_name | F32B5.8a | ||||||||
F32B5.8a.1 | |||||||||
CE36646 | |||||||||
F32B5.8b | |||||||||
CE50019 | |||||||||
F32B5.8b.1 | |||||||||
Other_name | CELE_F32B5.8 | Accession_evidence | NDB | BX284601 | |||||
Public_name | cpz-1 | ||||||||
DB_info | Database | AceView | gene | 1D256 | |||||
WormQTL | gene | WBGene00000788 | |||||||
WormFlux | gene | WBGene00000788 | |||||||
NDB | locus_tag | CELE_F32B5.8 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000788|UniProtKB=G5EGP8 | |||||||
family | PTHR12411 | ||||||||
NCBI | gene | 171829 | |||||||
RefSeq | protein | NM_058622.7 | |||||||
NM_001377810.2 | |||||||||
KEGG | KEGG_id | 3.4.18.1 | |||||||
NemaPath | KEGG_id | 3.4.18.1 | |||||||
SwissProt | UniProtAcc | G5EGP8 | |||||||
UniProt_GCRP | UniProtAcc | G5EGP8 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cpz | ||||||||
Allele (65) | |||||||||
Strain | WBStrain00031453 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (19) | |||||||||
Ortholog (34) | |||||||||
Paralog (28) | |||||||||
Structured_description | Concise_description | cpz-1 encodes a homolog of cathepsin z-like cysteine protease cyclicallyexpressed in hypodermal cells throughout development (along with adultgonad and pharynx) and required for normal molting; CPZ-1 protein ispresent in cuticle regions shortly before their degradation duringecydsis, and this expression pattern is conserved in Onchocerca volvulus;cpz-1(ok497) and cpz-1(RNAi) worms have defective molting, along withmisshapen heads and tails, defective gonads, and embryonic lethality. | Paper_evidence | WBPaper00006379 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 21 Aug 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; gonad morphogenesis; and post-embryonic development. Located in collagen and cuticulin-based cuticle extracellular matrix; extracellular space; and yolk granule. Expressed in several structures, including anterior hypodermis; cuticle; intestine; pharynx; and vulva. Is an ortholog of human CTSZ (cathepsin Z). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F32B5.8a | |||||||
F32B5.8b | |||||||||
Corresponding_CDS_history | F32B5.8:wp123 | ||||||||
Corresponding_transcript | F32B5.8a.1 | ||||||||
F32B5.8b.1 | |||||||||
Other_sequence (237) | |||||||||
Associated_feature | WBsf648984 | ||||||||
WBsf717464 | |||||||||
WBsf980972 | |||||||||
WBsf982941 | |||||||||
WBsf1009378 | |||||||||
WBsf219056 | |||||||||
Experimental_info | RNAi_result (12) | ||||||||
Expr_pattern | Expr2400 | ||||||||
Expr2892 | |||||||||
Expr2893 | |||||||||
Expr7868 | |||||||||
Expr1014352 | |||||||||
Expr1030489 | |||||||||
Expr1149993 | |||||||||
Expr2010522 | |||||||||
Expr2028762 | |||||||||
Drives_construct | WBCnstr00010810 | ||||||||
WBCnstr00011010 | |||||||||
WBCnstr00019867 | |||||||||
WBCnstr00037275 | |||||||||
Construct_product | WBCnstr00037275 | ||||||||
Antibody | WBAntibody00000710 | ||||||||
Microarray_results (18) | |||||||||
Expression_cluster (228) | |||||||||
Interaction (23) | |||||||||
Map_info | Map | I | Position | -7.97279 | Error | 0.169868 | |||
Positive | Positive_clone | F32B5 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4238 | |||||||
5249 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00006379 | ||||||||
WBPaper00010400 | |||||||||
WBPaper00027761 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00059755 | |||||||||
WBPaper00062444 | |||||||||
WBPaper00064339 | |||||||||
WBPaper00065026 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Homolog of Ov-cpz-1 | Paper_evidence | WBPaper00004821 | |||||||
Method | Gene |