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WormBase Tree Display for Gene: WBGene00000788

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Name Class

WBGene00000788EvidencePaper_evidenceWBPaper00004821
SMapS_parentSequenceF32B5
IdentityVersion1
NameCGC_namecpz-1
Sequence_nameF32B5.8
Molecular_nameF32B5.8a
F32B5.8a.1
CE36646
F32B5.8b
CE50019
F32B5.8b.1
Other_nameCELE_F32B5.8Accession_evidenceNDBBX284601
Public_namecpz-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpz
Allele (65)
StrainWBStrain00031453
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (34)
Paralog (28)
Structured_descriptionConcise_descriptioncpz-1 encodes a homolog of cathepsin z-like cysteine protease cyclicallyexpressed in hypodermal cells throughout development (along with adultgonad and pharynx) and required for normal molting; CPZ-1 protein ispresent in cuticle regions shortly before their degradation duringecydsis, and this expression pattern is conserved in Onchocerca volvulus;cpz-1(ok497) and cpz-1(RNAi) worms have defective molting, along withmisshapen heads and tails, defective gonads, and embryonic lethality.Paper_evidenceWBPaper00006379
Curator_confirmedWBPerson567
Date_last_updated21 Aug 2006 00:00:00
Automated_descriptionPredicted to enable cysteine-type endopeptidase activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; gonad morphogenesis; and post-embryonic development. Located in collagen and cuticulin-based cuticle extracellular matrix; extracellular space; and yolk granule. Expressed in several structures, including anterior hypodermis; cuticle; intestine; pharynx; and vulva. Is an ortholog of human CTSZ (cathepsin Z).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF32B5.8a
F32B5.8b
Corresponding_CDS_historyF32B5.8:wp123
Corresponding_transcriptF32B5.8a.1
F32B5.8b.1
Other_sequenceAIC00315_1
EL887816.1
MH08257
ACC01235_2
FK800718.1
FG976287.1
JO468425.1
EV852927.1
CBC01391_1
GPC02089_1
FE919468.1
JI180482.1
MHC02178_1
CB037656.1
TCC00354_1
EW744460.1
FK807124.1
XIC03298_1
EX556027.1
Tcol_isotig02599
FG970895.1
EX538176.1
FG970899.1
FD516887.1
FG979310.1
ASC08946_1
WBC01864_1
FF678722.1
FD515386.1
SS02537
EX561606.1
XI00367
FC546442.1
GP00402
FG975772.1
FC548680.1
GR19712
TX00296
ES570667.1
HC00273
FK800513.1
JI461610.1
EX912065.1
SSC04471_1
Oden_isotig12250
HO243982.1
PPC00032_1
TS02108
FG978529.1
FF681577.1
AF143817.1
FK800292.1
AYC04099_1
FD515227.1
XIC01144_1
FK803892.1
EV854231.1
EV853951.1
EV853544.1
ES566900.1
JI181209.1
SSC05254_1
CK850466.1
ES408944.1
Hbac_isotig00042
AW506285.1
DA02778
FK801879.1
CSC00016_1
CRC02134_1
ES561204.1
FK806706.1
RSC00694_1
JI478148.1
FG619912.1
FG976296.1
FK805999.1
CB038675.1
HBC00858_1
ES564509.1
PTC01745_1
FG980515.1
PTC02726_1
GRC00290_1
NAC00721_1
ES568456.1
EX542709.1
EX008166.1
Tcol_isotig14499
AW506343.1
FF679206.1
FK800036.1
EX500615.1
FF678746.1
EX009931.1
PP00024
FG977698.1
CJC15346_1
FK806438.1
FG976512.1
MIC05427_1
FK805557.1
Name_isotig04360
TS00471
PPC03129_1
EX553751.1
MH01652
FK806666.1
ES739074.1
HG08989
TSC00243_1
PSC01048_2
ACC01235_3
RS06064
GR14189
ES568646.1
GRC05203_1
ACC33650_1
FK802384.1
FD515268.1
JG463625.1
Oden_isotig12251
ES569158.1
TCC00321_1
FG972640.1
MIC05427_2
FK808862.1
EX012715.1
EX563252.1
Tcol_isotig02597
CR02418
FD514739.1
Tcol_isotig24286
MJC02751_1
FG971127.1
Hbac_isotig05486
CJC03564_1
CGC00569_1
EX549925.1
BXC01480_1
AS06359
TDC00768_1
FK803291.1
MJ03663
GE625260.1
MJ04266
SS02652
GRC00156_1
HBC10696_1
HCC03700_1
Tcir_isotig07258
HGC00200_1
FK804689.1
EX910429.1
FF680719.1
FG355575.1
EH005502.1
Acan_isotig06272
FG974724.1
GR19713
EX547867.1
ES413499.1
PT00482
FK804587.1
Tcol_isotig02596
ES741813.1
FF678442.1
AS17535
FK803316.1
FK800777.1
FG978843.1
FG971688.1
ACC01235_1
Tcol_isotig02598
HG03260
FF679294.1
MJ03677
HBC08275_1
FE918720.1
GR18484
EX500990.1
ES562885.1
DAC02221_1
FG974120.1
HC06581
MJ04258
DVC00940_1
FK804348.1
FF678379.1
BU665942.1
AE04645
EV853060.1
ES410435.1
AW505873.1
EW743024.1
EX553270.1
GE626135.1
GW408141.1
FG977227.1
MH10698
PTC03334_1
MI01866
FK809529.1
EZ421813.1
FK809350.1
Oden_isotig12252
HC00294
FK802900.1
ES567925.1
FG974669.1
JI459873.1
GO252244.1
XI01135
FC542629.1
FK806885.1
GR18485
EX011635.1
GT737421.1
ES411301.1
EX566941.1
FK800069.1
Dviv_contig23699
Acan_isotig06273
ES413256.1
CB038238.1
PVC03914_1
FG972321.1
PT00311
PT02831
U71150.1
FK803806.1
FG977536.1
FD517275.1
GO249857.1
JI177902.1
FK806102.1
FE915368.1
Associated_featureWBsf648984
WBsf717464
WBsf980972
WBsf982941
WBsf1009378
WBsf219056
Experimental_infoRNAi_result (12)
Expr_patternExpr2400
Expr2892
Expr2893
Expr7868
Expr1014352
Expr1030489
Expr1149993
Expr2010522
Expr2028762
Drives_constructWBCnstr00010810
WBCnstr00011010
WBCnstr00019867
WBCnstr00037275
Construct_productWBCnstr00037275
AntibodyWBAntibody00000710
Microarray_results (18)
Expression_cluster (228)
Interaction (23)
Map_infoMapIPosition-7.97279Error0.169868
PositivePositive_cloneF32B5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4238
5249
Pseudo_map_position
ReferenceWBPaper00006379
WBPaper00010400
WBPaper00027761
WBPaper00038491
WBPaper00055090
WBPaper00059755
WBPaper00062444
WBPaper00064339
WBPaper00065026
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
Homolog of Ov-cpz-1Paper_evidenceWBPaper00004821
MethodGene