WormBase Tree Display for Gene: WBGene00000535

WBGene00000535 SMap: S_parent: Sequence: K08B4
  Identity: Version: 2
    Name: CGC_name: cpi-1 Paper_evidence: WBPaper00026724
            WBPaper00005846
            WBPaper00024997
          Person_evidence: WBPerson4368
            WBPerson390
      Sequence_name: K08B4.6
      Molecular_name: K08B4.6
        K08B4.6.1
        CE18035
      Other_name: cli-2
        CELE_K08B4.6 Accession_evidence: NDB BX284604
      Public_name: cpi-1
    DB_info: Database: AceView gene 4G858
        WormQTL gene WBGene00000535
        WormFlux gene WBGene00000535
        NDB locus_tag CELE_K08B4.6
        Panther gene CAEEL|WormBase=WBGene00000535|UniProtKB=G5EDZ9
          family PTHR46186
        NCBI gene 177372
        RefSeq protein NM_068514.6
        SwissProt UniProtAcc G5EDZ9
        UniProt_GCRP UniProtAcc G5EDZ9
        OMIM gene 601891
            604312
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 04 Jan 2006 11:25:27 WBPerson2970 Name_change: CGC_name: cpi-1
                Other_name: cli-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpi
    Allele (20)
    Strain: WBStrain00031872
      WBStrain00054919
    RNASeq_FPKM (74)
    GO_annotation: 00015098
      00015099
      00015100
      00015101
      00015102
      00015103
      00015104
      00015105
      00015106
      00107561
    Ortholog (73)
    Paralog: WBGene00000534 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016523 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00023486 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cpi-1 encodes a homolog of cysteine protease inhibitors (cystatins); cpi-1 is at least superficially dispensable for viability and gross morphology. Paper_evidence: WBPaper00005654
            WBPaper00012890
          Curator_confirmed: WBPerson567
          Date_last_updated: 16 Jul 2007 00:00:00
      Automated_description: Enables cysteine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm; extracellular space; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of human CST1 (cystatin SN); CST3 (cystatin C); and CST4 (cystatin S). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (17)
  Molecular_info: Corresponding_CDS: K08B4.6
    Corresponding_transcript: K08B4.6.1
    Other_sequence (14)
    Associated_feature: WBsf651835
      WBsf230135
  Experimental_info: RNAi_result: WBRNAi00089361 Inferred_automatically: RNAi_primary
      WBRNAi00034106 Inferred_automatically: RNAi_primary
      WBRNAi00089116 Inferred_automatically: RNAi_primary
      WBRNAi00089348 Inferred_automatically: RNAi_primary
      WBRNAi00050231 Inferred_automatically: RNAi_primary
      WBRNAi00016775 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027924
      Expr1153925
      Expr2010489
      Expr2028729
    Drives_construct: WBCnstr00037466
    Construct_product: WBCnstr00037466
    Microarray_results (16)
    Expression_cluster (307)
    Interaction (190)
  Map_info: Map: IV Position: 2.96435 Error: 0.003526
    Positive: Positive_clone: K08B4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4900
    Pseudo_map_position
  Reference (13)
  Remark: Sequence connection from [Hashmi S, Lustigan S], [krb 020711]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    cpi-1 is also an other_name of cpin-1 (WBGene000000775) Person_evidence: WBPerson531
  Method: Gene