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WormBase Tree Display for Gene: WBGene00000534

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Name Class

WBGene00000534SMapS_parentSequenceR01B10
IdentityVersion2
NameCGC_namecpi-2Paper_evidenceWBPaper00026724
WBPaper00005846
WBPaper00024997
Person_evidenceWBPerson4368
WBPerson390
Sequence_nameR01B10.1
Molecular_nameR01B10.1a
R01B10.1a.1
CE25962
R01B10.1b
Other_namecli-1
CELE_R01B10.1Accession_evidenceNDBBX284605
Public_namecpi-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
204 Jan 2006 11:04:12WBPerson2970Name_changeCGC_namecpi-2
Other_namecli-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpi
Allele (30)
StrainWBStrain00031908
WBStrain00054915
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (48)
ParalogWBGene00000535Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016523Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00023486Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionAutomated_descriptionEnables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSR01B10.1a
Corresponding_transcriptR01B10.1b
R01B10.1a.1
Other_sequence (85)
Associated_featureWBsf028073
WBsf646851
WBsf655095
WBsf661303
WBsf661304
WBsf661305
WBsf1000163
WBsf231832
Experimental_infoRNAi_result (11)
Expr_patternExpr3711
Expr7868
Expr7869
Expr1020802
Expr1030320
Expr1154795
Expr2010490
Expr2028730
Drives_constructWBCnstr00012962
Construct_productWBCnstr00012962
AntibodyWBAntibody00001122
Microarray_results (31)
Expression_cluster (137)
InteractionWBInteraction000143932
WBInteraction000306622
WBInteraction000552020
WBInteraction000577508
Map_infoMapVPosition-0.400385Error0.008156
PositivePositive_cloneR01B10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4964
4240
Pseudo_map_position
Reference (12)
RemarkSequence connection from [Hashmi S, Lustigan S], [krb 020711]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene